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| Pronunciation |
 (LYE
doe kane trans OR
al) |
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| U.S. Brand Names |
| Dentipatch® |
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| Generic Available |
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No |
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| Pharmacological Index |
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Local Anesthetic, Transoral |
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| Use |
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Local anesthesia of the oral mucosa prior to oral injections and soft-tissue dental procedures |
|
| Contraindications |
|
Known hypersensitivity to any of its components |
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| Adverse Reactions |
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No data reported |
|
| Mechanism of Action |
|
Blocks both the initiation and conduction of nerve impulses by decreasing the neuronal membrane's permeability to sodium ions, which results in inhibition of depolarization with resultant blockade of conduction |
|
| Pharmacodynamics/Kinetics |
|
Onset of action: 2 minutes Duration of anesthesia after patch application: Based on 15-minute wear period, effect is present for at least 40 minutes |
|
| Usual Dosage |
|
One patch on selected area of oral mucosa |
|
| Dental Health: Local Anesthetic/Vasoconstrictor Precautions |
|
No information available to require special precautions |
|
| Dental Health: Effects on Dental Treatment |
|
No effects or complications reported |
|
| Dosage Forms |
|
Patch: 23 mg/2 cm2, 46.1 mg/2 cm2 (50s, 100s) |
|
| References |
|
Hersh EV, Houpt MI, Cooper SA, et al, "Analgesic Efficacy and Safety of an Intraoral Lidocaine Patch," J Am Dent Assoc, 1996, 127(11):1626-34. Houpt MI, Heins P, Lamster I, et al, "An Evaluation of Intraoral Lidocaine Patches in Reducing Needle-Insertion Pain," Compendium, 1997, 4:309-16. "The Lidocaine Patch: A New Delivery System," Biological Therapies in Dentistry, Sept 1997, vol 13. |
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