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Pronunciation |
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(EYE
oh di nay ted GLI ser
ole) |
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Generic
Available |
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Yes |
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Pharmacological Index |
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Expectorant |
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|
Use |
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Mucolytic expectorant in adjunctive treatment of bronchitis, bronchial
asthma, pulmonary emphysema, cystic fibrosis, or chronic
sinusitis |
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Pregnancy Risk
Factor |
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X |
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Contraindications |
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Hypersensitivity to inorganic iodides, iodinated glycerol, or any component;
pregnancy, newborns |
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Warnings/Precautions |
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Use with caution in patients with thyroid disease or renal
impairment |
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Adverse
Reactions |
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1% to 10%: Gastrointestinal: Diarrhea, nausea, vomiting
<1%: Headache, acne, dermatitis, acute parotitis, thyroid gland
enlargement, GI irritation, eyelid edema, pulmonary edema, hypersensitivity
|
|
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Overdosage/Toxicology |
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Symptoms include metallic taste, swollen eyelids, sneezing, nausea, vomiting,
diarrhea |
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Drug
Interactions |
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Increased toxicity: Disulfiram, metronidazole, procarbazine, MAO inhibitors,
CNS depressants, lithium |
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Mechanism of
Action |
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Increases respiratory tract secretions by decreasing surface tension and
thereby decreases the viscosity of mucus, which aids in removal of the
mucus |
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Pharmacodynamics/Kinetics |
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Absorption: From GI tract
Distribution: Accumulates in the thyroid gland
Elimination: In urine |
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Usual Dosage |
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Oral:
Adults: 60 mg 4 times/day |
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|
Test
Interactions |
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Thyroid function tests may be altered |
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Dental Health: Local
Anesthetic/Vasoconstrictor
Precautions |
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No information available to require special precautions |
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Dental Health:
Effects on Dental Treatment |
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No effects or complications reported |
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Patient
Information |
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Take with a full glass of water; not for use in coughs lasting longer than 1
week or associated with a fever |
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Nursing
Implications |
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Administer with plenty of fluids; elixir contains 21.75% alcohol; watch for
sedation; avoid elixir in children due to high alcohol
content |
|
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Dosage Forms |
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Organically bound iodine in brackets
Solution: 50 mg/mL [25 mg/mL] (30 mL)
Tablet: 30 mg [15 mg] |
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