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Hydrocodone and Chlorpheniramine
Pronunciation
U.S. Brand Names
Generic Available
Synonyms
Pharmacological Index
Use
Restrictions
Pregnancy Risk Factor
Adverse Reactions
Pharmacodynamics/Kinetics
Usual Dosage
Dental Health: Local Anesthetic/Vasoconstrictor Precautions
Dental Health: Effects on Dental Treatment
Patient Information
Nursing Implications
Dosage Forms

Pronunciation
(hye droe KOE done & klor fen IR a meen)

U.S. Brand Names
Tussionex®

Generic Available

Yes


Synonyms
Chlorpheniramine and Hydrocodone

Pharmacological Index

Antihistamine/Antitussive


Use

Symptomatic relief of cough and allergy


Restrictions

C-III


Pregnancy Risk Factor

C


Adverse Reactions

<1% (Limited to important or life-threatening symptoms): Drowsiness, sedation, lethargy, anxiety, facial pruritus, constipation, nausea, ureteral spasm, respiratory depression, dryness of pharynx


Pharmacodynamics/Kinetics

Duration: Hydrocodone: 4-6 hours


Usual Dosage

Oral:

Adults: 5 mL every 12 hours; do not exceed 10 mL/24 hours


Dental Health: Local Anesthetic/Vasoconstrictor Precautions

No information available to require special precautions


Dental Health: Effects on Dental Treatment

Prolonged use will cause significant xerostomia


Patient Information

Pregnancy precautions: Inform prescriber if you are or intend to be pregnant. Do not breast-feed.


Nursing Implications

Shake well before administering


Dosage Forms

Syrup, alcohol free: Hydrocodone polistirex 10 mg and chlorpheniramine polistirex 8 mg per 5 mL (480 mL, 900 mL)


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