|
Pronunciation |
|
(HEE
min) |
|
|
U.S. Brand
Names |
|
Panhematin® |
|
|
Generic
Available |
|
No |
|
|
Pharmacological Index |
|
Blood Modifiers |
|
|
Use |
|
Treatment of recurrent attacks of acute intermittent porphyria (AIP) only
after an appropriate period of alternate therapy has been
tried |
|
|
Contraindications |
|
Porphyria cutanea tarda; hypersensitivity to hemin |
|
|
Adverse
Reactions |
|
1% to 10%:
Hematologic: Leukocytosis
Local: Phlebitis |
|
|
Drug
Interactions |
|
Estrogens, barbiturates, corticosteroids, anticoagulants |
|
|
Usual Dosage |
|
I.V.: 1-4 mg/kg/day administered over 10-15 minutes for 3-14 days; may be
repeated no earlier than every 12 hours; not to exceed 6 mg/kg in any 24-hour
period |
|
|
Mental Health: Effects
on Mental Status |
|
None reported |
|
|
Mental Health:
Effects on Psychiatric
Treatment |
|
Avoid concurrent use with barbiturates |
|
|
Dental Health: Local
Anesthetic/Vasoconstrictor
Precautions |
|
No information available to require special precautions |
|
|
Dental Health:
Effects on Dental Treatment |
|
No effects or complications reported |
|
|
Dosage Forms |
|
Powder for injection, preservative free: 313 mg/vial [hematin 7 mg/mL] (43
mL) |
|
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