No

Corticosteroid, Topical

Relief of inflammatory and pruritic manifestations of corticosteroid-response dermatoses [very high potency topical corticosteroid]

C

Hypersensitivity to halobetasol or any component; viral, fungal, or tubercular skin lesions

Not for ophthalmic use; may cause adrenal suppression or insufficiency; application to abraded or inflamed areas or too large areas of the body may increase the risk of systemic absorption and the risk of adrenal suppression, as may prolonged use or the use of >50 g/week. Topical halobetasol should not be used for the treatment of rosacea or perioral dermatitis.

<1%: Itching, dry skin, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, skin maceration, skin atrophy, striae; local burning, irritation, miliaria; secondary infection

When consumed in excessive quantities, systemic hypercorticism and adrenal suppression may occur; in those cases, discontinuation and withdrawal of the corticosteroid should be done judiciously

No data reported

Corticosteroids inhibit the initial manifestations of the inflammatory process (ie, capillary dilation and edema, fibrin deposition, and migration and diapedesis of leukocytes into the inflamed site) as well as later sequelae (angiogenesis, fibroblast proliferation)

Absorption: Percutaneous absorption varies by location of topical application and the use of occlusive dressings; ~3% of a topically applied dose of ointment enters the circulation within 96 hours

Metabolism: Primarily in the liver

Elimination: By the kidneys

Children and Adults: Topical: Apply sparingly to skin twice daily, rub in gently and completely; treatment should not exceed 2 consecutive weeks and total dosage should not exceed 50 g/week. Therapy should be discontinued when control is achieved; if no improvement is seen, reassessment of diagnosis may be necessary.

None noted

None noted

No information available to require special precautions

No effects or complications reported

A thin film of cream or ointment is effective; do not overuse; do not use tight-fitting diapers or plastic pants on children being treated in the diaper area; use only as prescribed, and for no longer than the period prescribed; apply sparingly in light film; rub in lightly; avoid contact with eyes; notify physician if condition being treated persists or worsens

A thin film of cream or ointment is effective; do not overuse; do not use tight-fitting diapers or plastic pants on children being treated in the diaper area; use only as prescribed, and for no longer than the period prescribed; apply sparingly in light film; rub in lightly; avoid contact with eyes; notify physician if condition being treated persists or worsens

Cream, as propionate: 0.05% (15 g, 45 g)

Ointment, topical, as propionate: 0.05% (15 g, 45 g)