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Guaifenesin and Pseudoephedrine
Pronunciation
U.S. Brand Names
Generic Available
Synonyms
Pharmacological Index
Use
Pregnancy Risk Factor
Usual Dosage
Dental Health: Local Anesthetic/Vasoconstrictor Precautions
Dental Health: Effects on Dental Treatment
Patient Information
Dosage Forms

Pronunciation
(gwye FEN e sin & soo doe e FED rin)

U.S. Brand Names
Congess® Jr; Congess® Sr; Congestac®; Deconsal® II; Defen-LA®; Entex® PSE; Eudal-SR®; Fedahist® Expectorant [OTC]; Fedahist® Expectorant Pediatric [OTC]; Glycofed®; Guaifed®[OTC]; Guaifed-PD®; Guaifenex® PSE; GuaiMAX-D®; Guaitab®; Guaivent®; Guai-Vent/PSE®; Guiatuss PE®[OTC]; Halotussin® PE [OTC]; Histalet® X; Nasabid™; Respa-1st®; Respaire®-60 SR; Respaire®-120 SR; Robitussin-PE®[OTC]; Robitussin® Severe Congestion Liqui-Gels®[OTC]; Ru-Tuss® DE; Rymed®; Sinufed® Timecelles®; Touro LA®; Tuss-LA®; V-Dec-M®; Versacaps®; Zephrex®; Zephrex LA®

Generic Available

Yes


Synonyms
Pseudoephedrine and Guaifenesin

Pharmacological Index

Decongestant; Expectorant


Use

Enhance the output of respiratory tract fluid and reduce mucosal congestion and edema in the nasal passage


Pregnancy Risk Factor

C


Usual Dosage

Oral:

2-6 years: 2.5 mL every 4 hours not to exceed 15 mL/24 hours

6-12 years: 5 mL every 4 hours not to exceed 30 mL/24 hours

Children >12 years and Adults: 10 mL every 4 hours not to exceed 60 mL/24 hours


Dental Health: Local Anesthetic/Vasoconstrictor Precautions

Use with caution since pseudoephedrine is a sympathomimetic amine which could interact with epinephrine to cause a pressor response


Dental Health: Effects on Dental Treatment

Guaifenesin: No effects or complications reported

Pseudoephedrine: Up to 10% of patients could experience tachycardia, palpitations, and dry mouth; use vasoconstrictor with caution


Patient Information

See individual agents. Pregnancy/breast-feeding precautions: Inform prescriber if you are or intend to get pregnant. Consult prescriber if breast-feeding.


Dosage Forms

Capsule:

Guai-Vent™: Guaifenesin 250 mg and pseudoephedrine hydrochloride 120 mg

Robitussin® Severe Congestion Liqui-Gels®: Guaifenesin 200 mg and pseudoephedrine hydrochloride 30 mg

Rymed®: Guaifenesin 250 mg and pseudoephedrine hydrochloride 30 mg

Capsule, extended release:

Congess® Jr: Guaifenesin 125 mg and pseudoephedrine hydrochloride 60 mg

Nasabid®: Guaifenesin 250 mg and pseudoephedrine hydrochloride 90 mg

Congess® Sr, Guaifed®, Respaire®-120 SR: Guaifenesin 250 mg and pseudoephedrine hydrochloride 120 mg

Guaifed-PD®, Sinufed® Timecelles®, Versacaps®: Guaifenesin 300 mg and pseudoephedrine hydrochloride 60 mg

Respaire®-60 SR: Guaifenesin 200 mg and pseudoephedrine hydrochloride 60 mg

Tuss-LA® Capsule: Guaifenesin 500 mg and pseudoephedrine hydrochloride 120 mg

Drops, oral (Fedahist® Expectorant Pediatric): Guaifenesin 40 mg and pseudoephedrine hydrochloride 7.5 mg per mL (30 mL)

Syrup:

Fedahist® Expectorant, Guaifed®: Guaifenesin 200 mg and pseudoephedrine hydrochloride 30 mg per 5 mL (120 mL, 240 mL)

Guiatuss® PE, Halotussin® PE, Robitussin-PE®, Rymed®: Guaifenesin 100 mg and pseudoephedrine hydrochloride 30 mg per 5 mL (120 mL, 240 mL, 480 mL)

Histalet® X: Guaifenesin 200 mg and pseudoephedrine hydrochloride 45 mg per 5 mL (473 mL)

Tablet:

Congestac®, Guiatab®, Zephrex®: Guaifenesin 400 mg and pseudoephedrine hydrochloride 60 mg

Glycofed®: Guaifenesin 100 mg and pseudoephedrine hydrochloride 30 mg

Tablet, extended release:

Deconsal® II, Defen-L.A.®, Respa-1st®: Guaifenesin 600 mg and pseudoephedrine hydrochloride 60 mg

Entex® PSE, Guaifenex PSE®, GuaiMax-D®, Guai-Vent/PSE™, Ru-Tuss® DE, Sudex®, Zephrex LA®: Guaifenesin 600 mg and pseudoephedrine hydrochloride 120 mg

Eudal-SR®, Histalet® X, Touro LA®: Guaifenesin 400 mg and pseudoephedrine hydrochloride 120 mg

Tuss-LA® Tablet, V-Dec-M®: Guaifenesin 5 mg and pseudoephedrine hydrochloride 120 mg


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