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Creatine | ||
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Tyrosine | ||
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| Pronunciation |
 (gwye
FEN e sin & fen il proe pa
NOLE a meen) |
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| U.S. Brand Names |
| Ami-Tex LA®; Coldlac-LA®; Conex®[OTC]; Contuss® XT; Dura-Vent®; Entex® LA; Genagesic®; Genamin® Expectorant [OTC]; Guaifenex® PPA 75; Guaipax®; Myminic® Expectorant [OTC]; Naldecon-EX® Children's Syrup [OTC]; Nolex® LA; Partuss® LA; Phenylfenesin® L.A.; Profen II®; Profen LA®; Rymed-TR®; Silaminic® Expectorant [OTC]; Sildicon-E®[OTC]; Snaplets-EX®[OTC]; Triaminic® Expectorant [OTC]; Tri-Clear® Expectorant [OTC]; Triphenyl® Expectorant [OTC]; ULR-LA®; Vicks® DayQuil® Sinus Pressure & Congestion Relief [OTC] |
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| Generic Available |
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Yes |
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| Synonyms |
| Phenylpropanolamine and Guaifenesin |
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| Pharmacological Index |
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Decongestant; Expectorant |
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| Use |
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Symptomatic relief of those respiratory conditions where tenacious mucous plugs and congestion complicate the problem such as sinusitis, pharyngitis, bronchitis, asthma, and as an adjunctive therapy in serous otitis media |
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| Pregnancy Risk Factor |
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C |
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| Usual Dosage |
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Oral: 2-6 years: 2.5 mL every 4 hours 6-12 years: 1/2 tablet every 12 hours or 5 mL every 4 hours Children >12 years and Adults: 1 tablet every 12 hours or 10 mL every 4 hours |
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| Dietary Considerations |
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Have patient drink water after each dose |
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| Dental Health: Local Anesthetic/Vasoconstrictor Precautions |
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Use with caution since phenylpropanolamine is a sympathomimetic amine which could interact with epinephrine to cause a pressor response |
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| Dental Health: Effects on Dental Treatment |
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Guaifenesin: No effects or complications reported Phenylpropanolamine: Up to 10% of patients could experience tachycardia, palpitations, and dry mouth; use vasoconstrictor with caution |
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| Patient Information |
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See individual agents. Pregnancy/breast-feeding precautions: Inform prescriber if you are or intend to get pregnant. Consult prescriber if breast-feeding. |
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| Nursing Implications |
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Do not crush or chew sustained release tablet |
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| Dosage Forms |
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Caplet: Vicks® DayQuil® Sinus Pressure & Congestion Relief: Guaifenesin 200 mg and phenylpropanolamine hydrochloride 25 mg Gentab-LA®, Rymed-TR®: Guaifenesin 400 mg and phenylpropanolamine hydrochloride 75 mg Drops: Fedahist® Expectorant Pediatric: Guaifenesin 40 mg and phenylpropanolamine hydrochloride 7.5 mg per mL (30 mL) Sildicon-E®: Guaifenesin 30 mg and phenylpropanolamine hydrochloride 6.25 mg per mL (30 mL) Granules (Snaplets-EX®): Guaifenesin 50 mg and phenylpropanolamine hydrochloride 6.25 mg (pack) Liquid: Conex®, Genamin® Expectorant, Myminic® Expectorant, Silaminic® Expectorant, Theramine® Expectorant, Triaminic® Expectorant, Tri-Clear® Expectorant, Triphenyl® Expectorant: Guaifenesin 100 mg and phenylpropanolamine hydrochloride 12.5 mg per 5 mL (120 mL, 240 mL, 480 mL, 3780 mL) Naldecon-EX® Children's Syrup: Guaifenesin 100 mg and phenylpropanolamine hydrochloride 6.25 mg per 5 mL (120 mL) Tablet, extended release: Ami-Tex LA®, Contuss® XT, Entex® LA, Guaipax®, Nolex® LA, Partuss® LA, Phenylfenesin® L.A., ULR-LA®: Guaifenesin 400 mg and phenylpropanolamine hydrochloride 75 mg Dura-Vent®, Profen-LA®: Guaifenesin 600 mg and phenylpropanolamine hydrochloride 75 mg Coldloc-LA®, Guaifenex® PPA 75, Profen II®: Guaifenesin 600 mg and phenylpropanolamine hydrochloride 37.5 mg |
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