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Pronunciation |
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(JEN
shun VYE oh
let) |
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Generic
Available |
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Yes |
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Synonyms |
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Crystal Violet; Methylrosaniline Chloride |
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Pharmacological Index |
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Antibacterial, Topical; Antifungal Agent, Topical |
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|
Use |
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Treatment of cutaneous or mucocutaneous infections caused by Candida
albicans and other superficial skin infections |
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Pregnancy Risk
Factor |
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C |
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Contraindications |
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Known hypersensitivity to gentian violet; ulcerated areas; patients with
porphyria |
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Warnings/Precautions |
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Infants should be turned face down after application to minimize amount of
drug swallowed; may result in tattooing of the skin when applied to granulation
tissue; solution is for external use only; avoid contact with
eyes |
|
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Adverse
Reactions |
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1% to 10%: Esophagitis, burning, irritation, vesicle formation, sensitivity
reactions, ulceration of mucous membranes, laryngitis, tracheitis, laryngeal
obstruction |
|
|
Overdosage/Toxicology |
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Signs and symptoms: Laryngeal obstruction |
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Drug
Interactions |
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No data reported |
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Mechanism of
Action |
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Topical antiseptic/germicide effective against some vegetative gram-positive
bacteria, particularly Staphylococcus sp, and some yeast; it is much
less effective against gram-negative bacteria and is ineffective against
acid-fast bacteria |
|
|
Usual Dosage |
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Children and Adults: Topical: Apply 0.5% to 2% locally with cotton to lesion
2-3 times/day for 3 days, do not swallow and avoid contact with eyes
Adults: Intravaginal: Insert one tampon for 3-4 hours once or twice daily for
12 days |
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|
Dental Health: Local
Anesthetic/Vasoconstrictor
Precautions |
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No information available to require special precautions |
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|
Dental Health:
Effects on Dental Treatment |
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No effects or complications reported |
|
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Patient
Information |
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Drug stains skin and clothing purple; do not apply to an ulcerative lesion;
may result in "tattooing" of the skin; when used for the treatment of vaginal
candidiasis, coitus should be avoided; insert vaginal product high into vagina.
Use condoms or refrain from sexual intercourse to avoid
reinfection. |
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Dosage Forms |
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Solution, topical: 1% (30 mL); 2% (30 mL)
Tampons: 5 mg (12s) |
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