No

Antispasmodic Agent, Urinary

Antispasmodic to provide symptomatic relief of dysuria, nocturia, suprapubic pain, urgency, and incontinence due to detrusor instability and hyper-reflexia in elderly with cystitis, urethritis, urethrocystitis, urethrotrigonitis, and prostatitis

B

Pyloric or duodenal obstruction, GI hemorrhage, GI obstruction; ileus; achalasia; obstructive uropathies of lower urinary tract (BPH)

May cause drowsiness, vertigo, and ocular disturbances; administer cautiously in patients with suspected glaucoma

>10%:

Central nervous system: Drowsiness

Gastrointestinal: Xerostomia, dry throat

1% to 10%:

Cardiovascular: Tachycardia, palpitations,

Central nervous system: Nervousness, fatigue, vertigo, headache, hyperpyrexia

Gastrointestinal: Constipation, nausea, vomiting

<1%: Confusion (especially in the elderly), rash, leukopenia, increased intraocular pressure

Symptoms of overdose include clumsiness, dizziness, drowsiness, flushing, hallucinations, irritability

Supportive care only

No data reported

Synthetic antispasmotic with similar actions to that of propantheline; it exerts a direct relaxant effect on smooth muscles via phosphodiesterase inhibition, providing relief to a variety of smooth muscle spasms; it is especially useful for the treatment of bladder spasticity, whereby it produces an increase in urinary capacity

Onset of action: 55-60 minutes

Metabolism: To methyl; flavone carboxylic acid active

Elimination: 10% to 30% of dose excreted in urine within 6 hours

Children >12 years and Adults: Oral: 100-200 mg 3-4 times/day; reduce the dose when symptoms improve

Should be administered with water on an empty stomach

Monitor I & O closely

Drowsiness is common; may cause nervousness

None reported

No information available to require special precautions

>10% of patients experience dry mouth

Take exactly as directed, with water, preferably on an empty stomach (1 hour before or 2 hours after meals). Do not use alcohol or OTC medications without consulting prescriber. You may experience mild drowsiness, nervousness, or dizziness (use caution when driving or engaging in tasks requiring alertness until response to drug is known); nausea, vomiting, dry mouth (small frequent meals, frequent oral care, chewing gum, or sucking hard candy may help); decreased ability to perspire (avoid extremes of heat); constipation (increased exercise or dietary fluid and fiber may help). Report vision changes (blurred vision); rapid heartbeat; or unresolved nausea, vomiting, or constipation. Breast-feeding precautions: Consult prescriber if breast-feeding.

Monitor I & O closely, incontinence, and PVR

Tablet, film coated, as hydrochloride: 100 mg