Interactions with supplements
Calcium
Magnesium
Vitamin D
Vitamin E
Zinc
Look Up > Drugs > Estradiol and Testosterone
Estradiol and Testosterone
Pronunciation
U.S. Brand Names
Generic Available
Synonyms
Pharmacological Index
Use
Pregnancy Risk Factor
Contraindications
Adverse Reactions
Usual Dosage
Administration
Mental Health: Effects on Mental Status
Mental Health: Effects on Psychiatric Treatment
Dental Health: Local Anesthetic/Vasoconstrictor Precautions
Dental Health: Effects on Dental Treatment
Dosage Forms

Pronunciation
(es tra DYE ole & tes TOS ter one)

U.S. Brand Names
Andro/Fem® Injection; Deladumone® Injection; depAndrogyn® Injection; Depo-Testadiol® Injection; Depotestogen® Injection; Duo-Cyp® Injection; Duratestrin® Injection; Valertest No.1® Injection

Generic Available

No


Synonyms
Estradiol Cypionate and Testosterone Cypionate; Estradiol Valerate and Testosterone Enanthate; Testosterone and Estradiol

Pharmacological Index

Estrogen Derivative


Use

Vasomotor symptoms associated with menopause; postpartum breast engorgement


Pregnancy Risk Factor

X


Contraindications

Thromboembolic disorders; active arterial thrombosis; thyroid dysfunction; blood dyscrasias; hypersensitivity to estradiol or testosterone


Adverse Reactions

1% to 10%:

Central nervous system: Stroke, depression, dizziness, anxiety, headache, migraine

Dermatologic: Chloasma, melasma, rash

Endocrine & metabolic: Alterations in frequency and flow of menses, breast tenderness or enlargement, decreased glucose tolerance, increased triglycerides and LDL

Gastrointestinal: Nausea, GI distress

Hepatic: Cholestatic jaundice

Miscellaneous: Increased susceptibility to Candida infection


Usual Dosage

Adults: All dosage needs to be adjusted based upon the patient's response


Administration

For intramuscular use only


Mental Health: Effects on Mental Status

May cause anxiety or depression


Mental Health: Effects on Psychiatric Treatment

None reported


Dental Health: Local Anesthetic/Vasoconstrictor Precautions

No information available to require special precautions


Dental Health: Effects on Dental Treatment

No effects or complications reported


Dosage Forms

Injection:

Androgyn L.A.®, Deladumone®, Estra-Testrin®, Valertest No.1®: Estradiol valerate 4 mg and testosterone enanthate 90 mg per mL in sesame oil (5 mL, 10 mL)


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