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Pronunciation |
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(e
NAL a pril & dil TYE a
zem) |

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U.S. Brand
Names |
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Teczem® |

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Generic
Available |
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No |

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Pharmacological Index |
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Antihypertensive Agent, Combination |

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Use |
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Treatment of hypertension, however, not indicated for initial treatment of
hypertension; replacement therapy in patients receiving separate dosage forms
(for patient convenience); when monotherapy with one component fails to achieve
desired antihypertensive effect, or when dose-limiting adverse effects limit
upward titration of monotherapy |

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Pregnancy Risk
Factor |
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C/D (2nd and 3rd trimesters) |

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Usual Dosage |
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Adults: Oral: One tablet daily, if further blood pressure control is
required, increase dosage to two tablets daily |

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Cardiovascular
Considerations |
|
Combination therapy for the treatment of hypertension should be
individualized for each patient. Potential advantages for enalapril and
diltiazem combination therapy may include improved compliance and synergistic
reductions in blood pressure with an accompanied reduction in side
effects. |

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Dental Health: Local
Anesthetic/Vasoconstrictor
Precautions |
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No information available to require special precautions |

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Dental Health:
Effects on Dental Treatment |
|
Calcium channel blockers cause gingival hyperplasia in approximately 1% of
patients. There have been fewer reports with felodipine than with other CCBs.
The hyperplasia will disappear with cessation of drug therapy. Consultation with
physician is suggested. |

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Patient
Information |
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See individual agents. Pregnancy/breast-feeding precautions: Inform
prescriber if you are or intend to be pregnant. Consult prescriber if
breast-feeding. |

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Dosage Forms |
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Tablet, extended release: Enalapril maleate 5 mg and diltiazem maleate 180
mg |

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