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Docusate and Casanthranol
Pronunciation
U.S. Brand Names
Generic Available
Synonyms
Pharmacological Index
Use
Pregnancy Risk Factor
Adverse Reactions
Stability
Usual Dosage
Dental Health: Local Anesthetic/Vasoconstrictor Precautions
Dental Health: Effects on Dental Treatment
Patient Information
Nursing Implications
Dosage Forms

Pronunciation
(DOK yoo sate & ka SAN thra nole)

U.S. Brand Names
Dialose® Plus Capsule [OTC]; Diocto C®[OTC]; Diocto-K Plus®[OTC]; Dioctolose Plus®[OTC]; Disanthrol®[OTC]; DSMC Plus®[OTC]; Genasoft® Plus [OTC]; Peri-Colace®[OTC]; Pro-Sof® Plus [OTC]; Regulace®[OTC]; Silace-C®[OTC]

Generic Available

Yes


Synonyms
Casanthranol and Docusate; DSS With Casanthranol

Pharmacological Index

Laxative/Stool Softner


Use

Treatment of constipation generally associated with dry, hard stools and decreased intestinal motility


Pregnancy Risk Factor

C


Adverse Reactions

1% to 10%:

Gastrointestinal: Intestinal obstruction, diarrhea, abdominal cramping, throat irritation


Stability

Store in tight, light-resistant containers


Usual Dosage

Oral:

Adults: 1-2 capsules or 15-30 mL syrup at bedtime, may be increased to 2 capsules or 30 mL twice daily or 3 capsules at bedtime


Dental Health: Local Anesthetic/Vasoconstrictor Precautions

No information available to require special precautions


Dental Health: Effects on Dental Treatment

No effects or complications reported


Patient Information

Adults: Take with a full glass of water; patients should assure proper dietary fiber and fluid intake with adequate exercise if medically appropriate; do not use if abdominal pain, nausea, or vomiting are present; laxative use should be used for a short period of time (<1 week); prolonged use may result in abuse, dependence, as well as fluid and electrolyte loss; notify physician if bleeding occurs or if constipation is not relieved


Nursing Implications

Monitor bowel frequency


Dosage Forms

Capsule:

Dialose® Plus, Diocto-K Plus®, Dioctolose Plus®, DSMC Plus®: Docusate potassium 100 mg and casanthranol 30 mg

Disanthrol®, Genasoft® Plus, Peri-Colace®, Pro-Sof® Plus, Regulace®: Docusate sodium 100 mg and casanthranol 30 mg

Syrup (Diocto C®, Peri-Colace®, Silace-C®): Docusate sodium 60 mg and casanthranol 30 mg per 15 mL with alcohol 10% (240 mL, 480 mL, 4000 mL)


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