Look Up > Drugs > Dichlorphenamide
Dichlorphenamide
Pronunciation
U.S. Brand Names
Generic Available
Synonyms
Pharmacological Index
Use
Pregnancy Risk Factor
Contraindications
Adverse Reactions
Drug Interactions
Usual Dosage
Mental Health: Effects on Mental Status
Mental Health: Effects on Psychiatric Treatment
Dental Health: Local Anesthetic/Vasoconstrictor Precautions
Dental Health: Effects on Dental Treatment
Patient Information
Nursing Implications
Dosage Forms

Pronunciation
(dye klor FEN a mide)

U.S. Brand Names
Daranide®

Generic Available

No


Synonyms
Diclofenamide

Pharmacological Index

Carbonic Anhydrase Inhibitor; Diuretic, Carbonic Anhydrase Inhibitor; Ophthalmic Agent, Antiglaucoma


Use

Adjunct in treatment of open-angle glaucoma and perioperative treatment for angle-closure glaucoma


Pregnancy Risk Factor

C


Contraindications

Severe pulmonary obstruction; severe renal impairment; hypersensitivity to dichlorphenamide


Adverse Reactions

>10%:

Central nervous system: Fatigue, malaise

Gastrointestinal: Diarrhea, anorexia, metallic taste

Genitourinary: Polyuria

1% to 10%:

Central nervous system: Mental depression, drowsiness

Renal: Renal calculi


Drug Interactions

Increased lithium excretion and altered excretion of other drugs by alkalinization of the urine


Usual Dosage

Adults: Oral: 100-200 mg to start followed by 100 mg every 12 hours until desired response is obtained; maintenance dose: 25-50 mg 1-3 times/day


Mental Health: Effects on Mental Status

Sedation is common; may cause depression


Mental Health: Effects on Psychiatric Treatment

May rarely cause bone marrow suppression; use caution with clozapine and carbamazepine; may increase the excretion of lithium but should not be used to treat lithium toxicity


Dental Health: Local Anesthetic/Vasoconstrictor Precautions

No information available to require special precautions


Dental Health: Effects on Dental Treatment

No effects or complications reported


Patient Information

Report numbness or tingling of extremities to physician; ability to perform tasks requiring mental alertness and/or physical coordination may be impaired; take with food if GI upset occurs; notify if flank pain or rash occurs


Nursing Implications

Monitor electrolytes


Dosage Forms

Tablet: 50 mg


Copyright © 1978-2000 Lexi-Comp Inc. All Rights Reserved