Yes

Local Anesthetic

Dental: Amide derivative local anesthetic for minor skin conditions

Medical: Fast, temporary relief of pain and itching due to hemorrhoids, minor burns

C

Known hypersensitivity to amide-type anesthetics, ophthalmic use

Avoid use in sensitive individuals

1% to 10%:

Dermatologic: Angioedema, contact dermatitis

No data reported

Darkens on light exposure

Local anesthetics bind selectively to the intracellular surface of sodium channels to block influx of sodium into the axon. As a result, depolarization necessary for action potential propagation and subsequent nerve function is prevented. The block at the sodium channel is reversible. When drug diffuses away from the axon, sodium channel function is restored and nerve propagation returns.

Onset of action: Within 15 minutes

Duration: 2-4 hours

Absorption: Poor through intact skin, but well absorbed through mucous membranes and excoriated skin

Children and Adults: Topical: Apply gently to the affected areas; no more than 30 g for adults or 7.5 g for children should be used in any 24-hour period

No information available to require special precautions

No effects or complications reported

If condition worsens or if symptoms persist for >7 days, stop using the ointment and consult a physician; wash hands after use

Do not use near the eyes or over denuded surfaces or blistered areas

Cream, topical: 0.5% (45 g)

Ointment, topical: 1% (30 g, 60 g, 454 g)