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Pronunciation |
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(deks
TRAN oh
mer) |
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U.S. Brand
Names |
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Debrisan®[OTC] |
|
|
Generic
Available |
|
No |
|
|
Pharmacological Index |
|
Topical Skin Product |
|
|
Use |
|
Clean exudative ulcers and wounds such as venous stasis ulcers, decubitus
ulcers, and infected traumatic and surgical wounds; no controlled studies have
found dextranomer to be more effective than conventional
therapy |
|
|
Pregnancy Risk
Factor |
|
C |
|
|
Contraindications |
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Deep fistulas, sinus tracts, hypersensitivity to any
component |
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|
Warnings/Precautions |
|
Do not use in deep fistulas or any area where complete removal is not
assured; do not use on dry wounds (ineffective); avoid contact with
eyes |
|
|
Adverse
Reactions |
|
1% to 10%:
Dermatologic: Maceration may occur, erythema
Hematologic: Bleeding |
|
|
Drug
Interactions |
|
No data reported |
|
|
Mechanism of
Action |
|
Dextranomer is a network of dextran-sucrose beads possessing a great many
exposed hydroxy groups; when this network is applied to an exudative wound
surface, the exudate is drawn by capillary forces generated by the swelling of
the beads, with vacuum forces producing an upward flow of exudate into the
network |
|
|
Usual Dosage |
|
Debride and clean wound prior to application; apply to affected area once or
twice daily in a 1/4
" layer; apply a dressing and seal on all four sides; removal should be done by
irrigation |
|
|
Dental Health: Local
Anesthetic/Vasoconstrictor
Precautions |
|
No information available to require special precautions |
|
|
Dental Health:
Effects on Dental Treatment |
|
No effects or complications reported |
|
|
Patient
Information |
|
Use exactly as directed; do not overuse. Clean wound as directed. Sprinkle
beads into or apply paste to 1/4" thickness. Change dressing 1-4 times/day
before dressing is completely dry to facilitate removal. Wash hands carefully
following application. Avoid contact with eyes or other nonulcerous tissue.
Report increased swelling, redness, rash, itching, signs of infection, worsening
of condition, or lack of healing. Pregnancy precautions: Inform
prescriber if you are or intend to be pregnant. |
|
|
Nursing
Implications |
|
Sprinkle beads into ulcer (or apply paste) to
1/4
" thickness; change dressings 1-4 times/day depending on drainage; change
dressing before it is completely dry to facilitate removal |
|
|
Dosage Forms |
|
Beads: 4 g, 25 g, 60 g, 120 g
Paste: 10 g foil packets |
|
|
References |
|
Chamberlain TM, Cali TJ, Cuzzell J, et al,
"Assessment and Management of Pressure Sores in Long-Term Care Facilities,"
Consult Pharm, 1992, 7(12):1328-40.
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