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| Pronunciation |
 (deks
brom fen EER a meen & soo
doe e FED rin) |
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| U.S. Brand Names |
| Disobrom®[OTC]; Disophrol® Chronotabs®[OTC]; Disophrol® Tablet [OTC]; Drixomed®; Drixoral®[OTC] |
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| Generic Available |
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Yes |
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| Synonyms |
| Pseudoephedrine and Dexbrompheniramine |
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| Pharmacological Index |
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Antihistamine/Decongestant Combination |
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| Use |
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Relief of symptoms of upper respiratory mucosal congestion in seasonal and perennial nasal allergies, acute rhinitis, rhinosinusitis and eustachian tube blockage |
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| Pregnancy Risk Factor |
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B |
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| Usual Dosage |
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Children >12 years and Adults: Oral: 1 tablet every 12 hours, may require 1 tablet every 8 hours |
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| Dietary Considerations |
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May be administered with food or water |
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| Dental Health: Local Anesthetic/Vasoconstrictor Precautions |
|
Use with caution since pseudoephedrine is a sympathomimetic amine which could interact with epinephrine to cause a pressor response |
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| Dental Health: Effects on Dental Treatment |
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Up to 10% of patients could experience tachycardia, palpitations, and dry mouth; use vasoconstrictor with caution |
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| Patient Information |
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Swallow whole, do not crush or chew |
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| Nursing Implications |
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Swallow whole, do not crush or chew |
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| Dosage Forms |
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Tablet (Disophrol®): Dexbrompheniramine maleate 2 mg and pseudoephedrine sulfate 60 mg Timed release (Disobrom®, Disophrol® Chrontabs®, Drixomed®, Drixoral®, Histrodrix®, Resporal®): Dexbrompheniramine maleate 6 mg and pseudoephedrine sulfate 120 mg |
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