No

Corticosteroid, Topical

Adjunctive therapy for inflammation in acute and chronic corticosteroid responsive dermatosis (low potency corticosteroid)

C

Known hypersensitivity to desonide, fungal infections, tuberculosis of skin, herpes simplex

Use with caution in patients with impaired circulation, skin infections

<1%: Itching, dry skin, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, skin maceration, skin atrophy, striae; local burning, irritation, miliaria; secondary infection

Symptoms of overdose include moon face, central obesity, hypertension, diabetes, hyperlipidemia, peptic ulcer, increased susceptibility to infection, electrolyte and fluid imbalance, psychosis, hallucinations. When consumed in excessive quantities, systemic hypercorticism and adrenal suppression may occur; in those cases discontinuation and withdrawal of the corticosteroid should be done judiciously.

No data reported

Stimulates the synthesis of enzymes needed to decrease inflammation, suppress mitotic activity, and cause vasoconstriction

Onset of effect: Commonly noted within 7 days of continued therapy

Absorption: Topical absorption extensive from the scalp, face, axilla and scrotum; adequate through epidermis on appendages; absorption can be increased with occlusion or the addition of penetrants (eg, urea, DMSO)

Metabolism: By the liver

Elimination: Primarily in urine

Children and Adults: Topical: Apply 2-4 times/day sparingly. Therapy should be discontinued when control is achieved; if no improvement is seen, reassessment of diagnosis may be necessary.

Do not use on open wounds; apply sparingly to occlusive dressings

No information available to require special precautions

No effects or complications reported

A thin film of cream or ointment is effective, do not overuse; rub in lightly; do not use tight-fitting diapers or plastic pants on children being treated in the diaper area; use only as prescribed and for no longer than the period prescribed; avoid contact with eyes; notify physician if condition being treated persists or worsens

For external use only; do not use on open wounds; apply sparingly to occlusive dressings; should not be used in the presence of open or weeping lesions

Cream, topical: 0.05% (15 g, 60 g)

Lotion: 0.05% (60 mL, 120 mL)

Ointment, topical: 0.05% (15 g, 60 g)