Children: Maintenance: Surgical levels of anesthesia may be maintained with
concentrations of 5.2% to 10% desflurane, with or without nitrous oxide
Adults: Titrate dose based on individual response; see table in the product
packaging for specific details; minimum alveolar concentration (MAC) should be
reduced in elderly patients
Induction: Frequent starting concentration 3%; increased in 0.5% to 1%
increments every 2-3 breaths; end tidal concentrations of 4% to 11% desflurane
with and without nitrous oxide produce anesthesia within 2-4 minutes
Maintenance: Surgical levels of anesthesia in adults may be maintained with
concentrations of 2.5% to 8.5% desflurane, with or without nitrous oxide
Note: Because of the higher vapor pressure and higher MAC of
desflurane, special vaporizer canisters must be used. Equipment is not
interchangeable with that for isoflurane.