Look Up > Drugs > Desflurane
Desflurane
Pronunciation
U.S. Brand Names
Generic Available
Pharmacological Index
Use
Pregnancy Risk Factor
Usual Dosage
Dosage Forms

Pronunciation
(des FLOO rane)

U.S. Brand Names
Suprane®

Generic Available

No


Pharmacological Index

General Anesthetic


Use

Induction or maintenance of anesthesia for adults in outpatient and inpatient surgery


Pregnancy Risk Factor

B


Usual Dosage

Children: Maintenance: Surgical levels of anesthesia may be maintained with concentrations of 5.2% to 10% desflurane, with or without nitrous oxide

Adults: Titrate dose based on individual response; see table in the product packaging for specific details; minimum alveolar concentration (MAC) should be reduced in elderly patients

Induction: Frequent starting concentration 3%; increased in 0.5% to 1% increments every 2-3 breaths; end tidal concentrations of 4% to 11% desflurane with and without nitrous oxide produce anesthesia within 2-4 minutes

Maintenance: Surgical levels of anesthesia in adults may be maintained with concentrations of 2.5% to 8.5% desflurane, with or without nitrous oxide

Note: Because of the higher vapor pressure and higher MAC of desflurane, special vaporizer canisters must be used. Equipment is not interchangeable with that for isoflurane.


Dosage Forms

Liquid: 240 mL


Copyright © 1978-2000 Lexi-Comp Inc. All Rights Reserved