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Pronunciation |
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(SYE
a nide AN tee dote
kit) |
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Generic
Available |
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Yes |
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Pharmacological Index |
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Antidote |
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Use |
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Treatment of cyanide poisoning |
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Usual Dosage |
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Cyanide poisoning: 0.3 mL ampul of amyl nitrite is crushed every minute and
vapor is inhaled for 15-30 seconds until an I.V. sodium nitrite infusion is
available. Following administration of 300 mg I.V. sodium nitrite, inject 12.5 g
sodium thiosulfate I.V. (over ~10 minutes), if needed; injection of both may be
repeated at 1/2
the original dose. |
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Nursing
Implications |
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Sodium nitrate infusion is limited by hypotension; sodium thiosulfate
infusion rate is 2.5-5 mL/minute |
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Dosage Forms |
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Kit: Sodium nitrite 300 mg/10 mL (#2); sodium thiosulfate 12.5 g/50 mL (#2);
amyl nitrite 0.3 mL (#12); also disposable syringes, stomach tube, tourniquet
and instructions |
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