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Pronunciation |
|
(kroe
TAM i
tonn) |
|
|
U.S. Brand
Names |
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Eurax®
Topical |
|
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Generic
Available |
|
No |
|
|
Pharmacological Index |
|
Scabicidal Agent |
|
|
Use |
|
Treatment of scabies ( Sarcoptes scabiei) and symptomatic treatment of
pruritus |
|
|
Pregnancy Risk
Factor |
|
C |
|
|
Contraindications |
|
Hypersensitivity to crotamiton or other components; patients who manifest a
primary irritation response to topical medications |
|
|
Warnings/Precautions |
|
Avoid contact with face, eyes, mucous membranes, and urethral meatus; do not
apply to acutely inflamed or raw skin; for external use
only |
|
|
Adverse
Reactions |
|
<1%: Local irritation, pruritus, contact dermatitis, warm
sensation |
|
|
Overdosage/Toxicology |
|
Symptoms of ingestion include burning sensation in mouth, irritation of the
buccal, esophageal and gastric mucosa, nausea, vomiting and abdominal pain
There is no specific antidote; general measures to eliminate the drug and
reduce its absorption, combined with symptomatic treatment, are recommended
|
|
|
Drug
Interactions |
|
No data reported |
|
|
Mechanism of
Action |
|
Crotamiton has scabicidal activity against Sarcoptes scabiei;
mechanism of action unknown |
|
|
Usual Dosage |
|
Topical:
Pruritus: Massage into affected areas until medication is completely
absorbed; repeat as necessary |
|
|
Dental Health: Local
Anesthetic/Vasoconstrictor
Precautions |
|
No information available to require special precautions |
|
|
Dental Health:
Effects on Dental Treatment |
|
No effects or complications reported |
|
|
Patient
Information |
|
For topical use only. Apply lotion to whole body from the chin down being
sure to cover all skin folds and creases. Apply a second application 24 hours
later. Avoid eyes. Take a bath 48 hours after application. All contaminated
clothing and bed linen should be washed to avoid reinfestation. If cure is not
achieved after 2 doses, use alternative therapy. Pregnancy/breast-feeding
precautions: Inform prescriber if you are or intend to be pregnant. Consult
prescriber if breast-feeding. |
|
|
Nursing
Implications |
|
Lotion: Shake well before using; avoid contact with face, eyes, mucous
membranes, and urethral meatus |
|
|
Dosage Forms |
|
Cream: 10% (60 g)
Lotion: 10% (60 mL, 454 mL) |
|
|
References |
|
Eichenfield LF, Honig PJ, "Blistering Disorders in Childhood," Pediatr
Clin North Am, 1991, 38(4):959-76.
Hogan DJ, Schachner L, Tanglertsampan C,
"Diagnosis and Treatment of Childhood Scabies and Pediculosis," Pediatr Clin
North Am, 1991, 38(4):941-57.
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