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Pronunciation |
|
(klor
tet ra SYE
kleen) |
|
|
U.S. Brand
Names |
|
Aureomycin® |
|
|
Generic
Available |
|
Yes |
|
|
Synonyms |
|
Chlortetracycline Hydrochloride |
|
|
Pharmacological Index |
|
Antibiotic, Ophthalmic; Antibiotic, Tetracycline Derivative; Antibiotic,
Topical |
|
|
Use |
|
Ophthalmic: Treatment of superficial ocular infections involving the
conjunctiva or cornea due to strains of susceptible microorganisms
Topical: Treatment of superficial infections of the skin due to susceptible
organisms, also infection prophylaxis in minor skin abrasions
|
|
|
Pregnancy Risk
Factor |
|
D |
|
|
Contraindications |
|
Hypersensitivity to tetracycline or any component; do not use topical
formulation in eyes |
|
|
Warnings/Precautions |
|
Prolonged use may cause superinfection; ophthalmic ointments may retard
corneal epithelial healing |
|
|
Adverse
Reactions |
|
1% to 10%: Dermatologic: Faint yellowing of skin
<1%: Edema, reddening of skin, photosensitivity, irritation
|
|
|
Drug
Interactions |
|
No data reported |
|
|
Mechanism of
Action |
|
Inhibits bacterial protein synthesis by binding with the 30S and possibly the
50S ribosomal subunit(s) of susceptible bacteria; may also cause alterations in
the cytoplasmic membrane; usually bacteriostatic, may be
bactericidal |
|
|
Usual Dosage |
|
Ophthalmic:
Acute infections: Instill
1/2
" (1.25 cm) every 3-4 hours until improvement
Mild to moderate infections: Instill
1/2
" (1.25 cm) 2-3 times/day
Topical: Apply 1-4 times/day, cover with sterile bandage if needed
|
|
|
Mental Health: Effects
on Mental Status |
|
None reported |
|
|
Mental Health:
Effects on Psychiatric
Treatment |
|
None reported |
|
|
Dental Health: Local
Anesthetic/Vasoconstrictor
Precautions |
|
No information available to require special precautions |
|
|
Dental Health:
Effects on Dental Treatment |
|
No effects or complications reported |
|
|
Patient
Information |
|
For ophthalmic use, tilt head back, place medication in conjunctival sac and
close eye, apply light finger pressure on lacrimal sac following instillation
Topical is for external use only, contact physician if rash or irritation
develops, may stain clothing |
|
|
Nursing
Implications |
|
Cleanse affected area of skin prior to application unless otherwise
directed |
|
|
Dosage Forms |
|
Ointment, ophthalmic, as hydrochloride: 1% [10 mg/g] (3.5
g) |
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