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| Pronunciation |
 (klor
fen IR a meen & soo doe e
FED rin) |
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| U.S. Brand Names |
| Allerest® Maximum Strength [OTC]; Anamine® Syrup [OTC]; Anaplex® Liquid [OTC]; Chlorafed® Liquid [OTC]; Chlor-Trimeton® 4 Hour Relief Tablet [OTC]; Co-Pyronil® 2 Pulvules®[OTC]; Deconamine® SR; Deconamine® Syrup [OTC]; Deconamine® Tablet [OTC]; Fedahist® Tablet [OTC]; Hayfebrol® Liquid [OTC]; Histalet® Syrup [OTC]; Klerist-D® Tablet [OTC]; Pseudo-Gest Plus® Tablet [OTC]; Rhinosyn® Liquid [OTC]; Rhinosyn-PD® Liquid [OTC]; Ryna® Liquid [OTC]; Sudafed® Plus Tablet [OTC] |
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| Generic Available |
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Yes |
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| Synonyms |
| Pseudoephedrine and Chlorpheniramine |
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| Pharmacological Index |
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Antihistamine/Decongestant Combination |
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| Use |
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Relief of nasal congestion associated with the common cold, hay fever, and other allergies, sinusitis, eustachian tube blockage, and vasomotor and allergic rhinitis |
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| Pregnancy Risk Factor |
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C |
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| Usual Dosage |
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Oral: Tablet: One 3-4 times/day |
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| Dental Health: Local Anesthetic/Vasoconstrictor Precautions |
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Use with caution since pseudoephedrine is a sympathomimetic amine which could interact with epinephrine to cause a pressor response |
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| Dental Health: Effects on Dental Treatment |
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Chlorpheniramine: Prolonged use will cause significant xerostomia Pseudoephedrine: Up to 10% of patients could experience tachycardia, palpitations, and dry mouth; use vasoconstrictor with caution; prolonged use will cause significant xerostomia |
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| Patient Information |
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May cause drowsiness. Alcohol may worsen this effect. Use caution while driving or operating machinery. |
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| Nursing Implications |
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Timesules® should not be chewed |
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| Dosage Forms |
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Capsule: Co-Pyronil® 2 Pulvules®: Chlorpheniramine maleate 4 mg and pseudoephedrine hydrochloride 60 mg Capsule, sustained release: Chlorpheniramine maleate 4 mg and pseudoephedrine hydrochloride 60 mg; chlorpheniramine maleate 8 mg and pseudoephedrine hydrochloride 120 mg Liquid: Anamine®, Anaplex®, Chlorafed®, Deconamine®, Hayfebrol®, Rhinosyn-PD®, Ryna®: Chlorpheniramine maleate 2 mg and pseudoephedrine sulfate 30 mg per 5 mL Rhinosyn®: Chlorpheniramine maleate 2 mg and pseudoephedrine sulfate 60 mg per 5 mL Histalet®: Chlorpheniramine maleate 3 mg and pseudoephedrine sulfate 45 mg per 5 mL Tablet: Allerest® Maximum Strength: Chlorpheniramine maleate 2 mg and pseudoephedrine hydrochloride 30 mg Deconamine®, Fedahist®, Klerist-D®, Pseudo-Gest Plus®, Sudafed® Plus: Chlorpheniramine maleate 4 mg and pseudoephedrine hydrochloride 60 mg Chlor-Trimeton® 4 Hour Relief: Chlorpheniramine maleate 4 mg and pseudoephedrine sulfate 60 mg |
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