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Pronunciation |
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(klor
fen IR a meen, soo doe e FED
rin, & KOE deen) |
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U.S. Brand
Names |
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Codehist® DH; Decohistine® DH;
Dihistine® DH; Ryna-C®
Liquid |
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Generic
Available |
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Yes |
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Pharmacological Index |
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Antihistamine/Decongestant/Antitussive |
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Use |
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Temporary relief of cough associated with minor throat or bronchial
irritation or nasal congestion due to common cold, allergic rhinitis, or
sinusitis |
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Restrictions |
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C-V |
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Pregnancy Risk
Factor |
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C |
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Adverse
Reactions |
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1% to 10%:
Central nervous system: Sedation, dizziness, drowsiness, increased
intracranial pressure
Gastrointestinal: Constipation, biliary tract spasm
Genitourinary: Urinary tract spasm
Miscellaneous: Physical or psychological dependence with continued use
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Usual Dosage |
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Oral:
25-50 lb: 1.25-2.50 mL every 4-6 hours, up to 4 doses in 24-hour period
50-90 lb: 2.5-5 mL every 4-6 hours, up to 4 doses in 24-hour period
Adults: 10 mL every 4-6 hours, up to 4 doses in 24-hour period
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Dental Health: Local
Anesthetic/Vasoconstrictor
Precautions |
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Use with caution since pseudoephedrine is a sympathomimetic amine which could
interact with epinephrine to cause a pressor response |
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Dental Health:
Effects on Dental Treatment |
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Chlorpheniramine: Prolonged use will cause significant xerostomia
Codeine: <1%: Dry mouth
Pseudoephedrine: Up to 10% of patients could experience tachycardia,
palpitations, and dry mouth; use vasoconstrictor with caution
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Dosage Forms |
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Liquid: Chlorpheniramine maleate 2 mg, pseudoephedrine hydrochloride 30 mg,
and codeine phosphate 10 mg (120 mL, 480
mL) |
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