| Pronunciation |
 (klor
FEN e
sin) |
 |
| U.S. Brand Names |
| Maolate® |
|
| Generic Available |
|
No |
|
| Synonyms |
| Chlorphenesin Carbamate |
|
| Pharmacological Index |
|
Skeletal Muscle Relaxant |
|
| Use |
|
Adjunctive treatment of discomfort in short-term, acute, painful musculoskeletal conditions |
|
| Pregnancy Risk Factor |
|
C |
|
| Contraindications |
|
Hypersensitivity to chlorphenesin |
|
| Adverse Reactions |
|
>10%: Central nervous system: Drowsiness 1% to 10%: Cardiovascular: Tachycardia, tightness in chest, flushing of face Central nervous system: Syncope, mental depression, dizziness lightheadedness, headache, paradoxical stimulation Dermatologic: Angioedema Gastrointestinal: Stomach cramps, hiccups, nausea, vomiting Neuromuscular & skeletal: Trembling Ocular: Burning of eyes Respiratory: Shortness of breath Miscellaneous: Allergic fever |
|
| Usual Dosage |
|
Adults: Oral: 800 mg 3 times/day, then adjusted to lowest effective dosage, usually 400 mg 4 times/day for up to a maximum of 2 months |
|
| Mental Health: Effects on Mental Status |
|
Drowsiness is common; may cause depression or paradoxical stimulation |
|
| Mental Health: Effects on Psychiatric Treatment |
|
May rarely produce aplastic anemia or leukopenia; use caution with clozapine and carbamazepine |
|
| Dental Health: Local Anesthetic/Vasoconstrictor Precautions |
|
No information available to require special precautions |
|
| Dental Health: Effects on Dental Treatment |
|
No effects or complications reported |
|
| Patient Information |
|
May cause drowsiness, may impair judgment and coordination; avoid alcohol and other CNS depressants |
|
| Nursing Implications |
|
May cause drowsiness, may impair judgment and coordination; avoid alcohol and other CNS depressants |
|
| Dosage Forms |
|
Tablet, as carbamate: 400 mg |
|
|
|
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