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Pronunciation |
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(KAS
tor
oyl) |

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U.S. Brand
Names |
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Alphamul®[OTC]; Emulsoil®[OTC];
Fleet® Flavored Castor Oil [OTC]; Neoloid®[OTC];
Purge®[OTC] |

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Generic
Available |
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Yes |

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Synonyms |
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Oleum Ricini |

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Pharmacological Index |
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Laxative, Miscellaneous |

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Use |
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Preparation for rectal or bowel examination or surgery; rarely used to
relieve constipation; also applied to skin as emollient and
protectant |

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Pregnancy Risk
Factor |
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X |

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Adverse
Reactions |
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1% to 10%:
Central nervous system: Dizziness
Endocrine & metabolic: Electrolyte disturbance
Gastrointestinal: Abdominal cramps, nausea, diarrhea
<1%: Pelvic congestion |

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Drug
Interactions |
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No data reported |

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Stability |
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Protect from heat (castor oil emulsion should be protected from
freezing) |

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Mechanism of
Action |
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Acts primarily in the small intestine; hydrolyzed to ricinoleic acid which
reduces net absorption of fluid and electrolytes and stimulates
peristalsis |

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Pharmacodynamics/Kinetics |
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Onset of action: Oral: 2-6 hours |

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Usual Dosage |
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Oral:
Children 2-11 years: 5-15 mL as a single dose
Children greater than or equal to 12 years and Adults: 15-60 mL as a single
dose
Emulsified:
36.4%:
Children <2 years: 5-15 mL/dose
Children 2-11 years: 7.5-30 mL/dose
Children greater than or equal to 12 years and Adults: 30-60 mL/dose
60% to 67%:
Children <2 years: 1.25-5 mL
Children 2-12 years: 5-15 mL
Adults: 15-45 mL
95%, mix with 1/2
to 1 full glass liquid:
Children: 5-10 mL
Adults: 15-60 mL |

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Dietary
Considerations |
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Should be administered on an empty stomach with juice or carbonated
beverages |

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Administration |
|
Do not administer at bedtime because of rapid onset of
action |

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Dental Health: Local
Anesthetic/Vasoconstrictor
Precautions |
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No information available to require special precautions |

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Dental Health:
Effects on Dental Treatment |
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No effects or complications reported |

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Patient
Information |
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Chill or take with juice or carbonated beverage to improve
taste |

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Nursing
Implications |
|
Do not administer at bedtime because of rapid onset of action; chill or
administer with juice or carbonated beverage to improve palatability
Monitor I & O, serum electrolytes, stool frequency |

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Dosage Forms |
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Emulsion, oral:
Alphamul®: 60% (90 mL, 3780 mL)
Emulsoil®: 95% (63 mL)
Fleet® Flavored Castor Oil: 67% (45 mL, 90 mL)
Neoloid®: 36.4% (118 mL)
Liquid, oral:
100% (60 mL, 120 mL, 480 mL)
Purge®: 95% (30 mL, 60 mL)
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