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Calcium Citrate
Pronunciation
U.S. Brand Names
Generic Available
Pharmacological Index
Use
Pregnancy Risk Factor
Contraindications
Adverse Reactions
Drug Interactions
Mechanism of Action
Pharmacodynamics/Kinetics
Usual Dosage
Mental Health: Effects on Mental Status
Mental Health: Effects on Psychiatric Treatment
Dental Health: Local Anesthetic/Vasoconstrictor Precautions
Dental Health: Effects on Dental Treatment
Patient Information
Nursing Implications
Dosage Forms

Pronunciation
(KAL see um SIT rate)

U.S. Brand Names
Citracal®[OTC]

Generic Available

No


Pharmacological Index

Calcium Salt


Use

Antacid; treatment and prevention of calcium deficiency or hyperphosphatemia (eg, osteoporosis, osteomalacia, mild/moderate renal insufficiency, hypoparathyroidism, postmenopausal osteoporosis, rickets)


Pregnancy Risk Factor

C


Contraindications

Hypercalcemia; renal calculi; ventricular fibrillation


Adverse Reactions

Mild hypercalcemia (calcium: >10.5 mg/dL) may be asymptomatic or manifest itself as constipation, anorexia, nausea, and vomiting

More severe hypercalcemia (calcium: >12 mg/dL) is associated with confusion, delirium, stupor, and coma

<1%:

Central nervous system: Headache

Endocrine & metabolic: Hypophosphatemia, hypercalcemia

Gastrointestinal: Nausea, anorexia, vomiting, abdominal pain, constipation

Miscellaneous: Thirst


Drug Interactions

Decreased effect:

Calcium citrate may significantly decrease the bioavailability of tetracyclines and fluoroquinolones, iron salts with salicylates

Large intakes of dietary fiber may decrease calcium absorption due to a decreased GI transit time and the formation of fiber-calcium complexes

Increased effect: Calcium citrate may increase the effects of quinidine


Mechanism of Action

Moderates nerve and muscle performance via action potential excitation threshold regulation


Pharmacodynamics/Kinetics

Absorption: From the GI tract requires vitamin D


Usual Dosage

Oral: Dosage is in terms of elemental calcium

<6 months: 360 mg/day

6-12 months: 540 mg/day

1-10 years: 800 mg/day

10-18 years: 1200 mg/day

Adults: 1-2 g/day

Dietary supplement: Usual dose: 500 mg to 2 g 2-4 times/day


Mental Health: Effects on Mental Status

May cause confusion and delirium (as a consequence of hypercalcemia)


Mental Health: Effects on Psychiatric Treatment

None reported


Dental Health: Local Anesthetic/Vasoconstrictor Precautions

No information available to require special precautions


Dental Health: Effects on Dental Treatment

No effects or complications reported


Patient Information

Chew tablets well, followed by water; do not take calcium supplements within 1-2 hours of taking other medicine by mouth or eating large amounts of fiber-rich foods; do not drink large amounts of alcohol or caffeine-containing beverages or use tobacco


Nursing Implications

Monitor serum calcium


Dosage Forms

Elemental calcium listed in brackets

Effervescent: 2376 mg [500 mg]


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