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Pronunciation |
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(KAL
see um SIT
rate) |
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U.S. Brand
Names |
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Citracal®[OTC] |
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Generic
Available |
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No |
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Pharmacological Index |
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Calcium Salt |
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Use |
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Antacid; treatment and prevention of calcium deficiency or hyperphosphatemia
(eg, osteoporosis, osteomalacia, mild/moderate renal insufficiency,
hypoparathyroidism, postmenopausal osteoporosis, rickets) |
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Pregnancy Risk
Factor |
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C |
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Contraindications |
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Hypercalcemia; renal calculi; ventricular fibrillation |
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Adverse
Reactions |
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Mild hypercalcemia (calcium: >10.5 mg/dL) may be asymptomatic or manifest
itself as constipation, anorexia, nausea, and vomiting
More severe hypercalcemia (calcium: >12 mg/dL) is associated with
confusion, delirium, stupor, and coma
<1%:
Central nervous system: Headache
Endocrine & metabolic: Hypophosphatemia, hypercalcemia
Gastrointestinal: Nausea, anorexia, vomiting, abdominal pain, constipation
Miscellaneous: Thirst |
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Drug
Interactions |
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Decreased effect:
Calcium citrate may significantly decrease the bioavailability of
tetracyclines and fluoroquinolones, iron salts with salicylates
Large intakes of dietary fiber may decrease calcium absorption due to a
decreased GI transit time and the formation of fiber-calcium complexes
Increased effect: Calcium citrate may increase the effects of quinidine
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Mechanism of
Action |
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Moderates nerve and muscle performance via action potential excitation
threshold regulation |
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Pharmacodynamics/Kinetics |
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Absorption: From the GI tract requires vitamin D |
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Usual Dosage |
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Oral: Dosage is in terms of elemental calcium
<6 months: 360 mg/day
6-12 months: 540 mg/day
1-10 years: 800 mg/day
10-18 years: 1200 mg/day
Adults: 1-2 g/day
Dietary supplement: Usual dose: 500 mg to 2 g 2-4 times/day
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Mental Health: Effects
on Mental Status |
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May cause confusion and delirium (as a consequence of
hypercalcemia) |
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Mental Health:
Effects on Psychiatric
Treatment |
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None reported |
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Dental Health: Local
Anesthetic/Vasoconstrictor
Precautions |
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No information available to require special precautions |
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Dental Health:
Effects on Dental Treatment |
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No effects or complications reported |
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Patient
Information |
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Chew tablets well, followed by water; do not take calcium supplements within
1-2 hours of taking other medicine by mouth or eating large amounts of
fiber-rich foods; do not drink large amounts of alcohol or caffeine-containing
beverages or use tobacco |
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Nursing
Implications |
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Monitor serum calcium |
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Dosage Forms |
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Elemental calcium listed in brackets
Effervescent: 2376 mg [500 mg]
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