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Pronunciation |
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(at
a PULL
gite) |
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U.S. Brand
Names |
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Children's Kaopectate®[OTC];
Diasorb®[OTC]; Kaopectate® Advanced Formula [OTC];
Kaopectate® Maximum Strength
Caplets; Rheaban®[OTC] |
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Generic
Available |
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Yes |
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Pharmacological Index |
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Antidiarrheal |
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Use |
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Symptomatic treatment of diarrhea |
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Pregnancy Risk
Factor |
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B |
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Contraindications |
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Hypersensitivity to attapulgite or any component |
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Adverse
Reactions |
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The powder, if chronically inhaled, can cause pneumoconiosis, since it
contains large amounts of silica |
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Drug
Interactions |
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Decreased GI absorption of orally administered clindamycin, tetracyclines,
penicillamine, digoxin |
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Mechanism of
Action |
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Controls diarrhea because of its absorbent action |
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Pharmacodynamics/Kinetics |
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Absorption: Not absorbed from GI tract |
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Usual Dosage |
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Oral:
<3 years: Not recommended
3-6 years: 750 mg/dose up to 2250 mg/24 hours
6-12 years: 1200-1500 mg/dose up to 4500 mg/24 hours
Adults: 1200-1500 mg after each loose bowel movement or every 2 hours; 15-30
mL up to 8 times/day, up to 9000 mg/24 hours |
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Mental Health: Effects
on Mental Status |
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None reported |
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Mental Health:
Effects on Psychiatric
Treatment |
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Concurrent use with psychotropics may produce additive GI effects
(constipation) |
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Dental Health: Local
Anesthetic/Vasoconstrictor
Precautions |
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No information available to require special precautions |
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Dental Health:
Effects on Dental Treatment |
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Do not give oral drugs concomitantly with Kaopectate®
due to decreased GI absorption |
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Patient
Information |
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If diarrhea is not controlled in 48 hours, contact a
physician |
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Nursing
Implications |
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Shake well before administering; re-evaluate cause of diarrhea if not
controlled in 48 hours; diarrhea should also be treated by diet, ie, clear
liquids, bland foods, and no dairy products for first 24-48 hours
Monitor for signs of fluid and electrolyte loss |
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Dosage Forms |
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Liquid, oral concentrate: 600 mg/15 mL (180 mL, 240 mL, 360 mL, 480 mL); 750
mg/15 mL (120 mL)
Tablet: 750 mg
Chewable: 300 mg, 600 mg |
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