Look Up > Drugs > Antipyrine and Benzocaine
Antipyrine and Benzocaine
Pronunciation
U.S. Brand Names
Generic Available
Synonyms
Pharmacological Index
Use
Pregnancy Risk Factor
Adverse Reactions
Usual Dosage
Dental Health: Local Anesthetic/Vasoconstrictor Precautions
Dental Health: Effects on Dental Treatment
Patient Information
Nursing Implications
Dosage Forms
References

Pronunciation
(an tee PYE reen & BEN zoe kane)

U.S. Brand Names
Allergan® Ear Drops; Auralgan®; Auroto®; Otocalm® Ear

Generic Available

Yes


Synonyms
Benzocaine and Antipyrine

Pharmacological Index

Otic Agent, Analgesic; Otic Agent, Cerumenolytic


Use

Temporary relief of pain and reduction of swelling associated with acute congestive and serous otitis media, swimmer's ear, otitis externa; facilitates ear wax removal


Pregnancy Risk Factor

C


Adverse Reactions

<1%:

Local: Burning, stinging, tenderness

Miscellaneous: Hypersensitivity reactions


Usual Dosage

Otic: Fill ear canal; moisten cotton pledget, place in external ear, repeat every 1-2 hours until pain and congestion is relieved; for ear wax removal instill drops 3-4 times/day for 2-3 days


Dental Health: Local Anesthetic/Vasoconstrictor Precautions

Information available to require special precautions


Dental Health: Effects on Dental Treatment

No effects or complications reported


Patient Information

For the ear


Nursing Implications

Use of otic anesthetics may mask symptoms of a fulminating middle ear infection (acute otitis media); not intended for prolonged use


Dosage Forms

Solution, otic: Antipyrine 5.4% and benzocaine 1.4% (10 mL, 15 mL)


References

Rodriguez LF, Smolik LM, and Zbehlik AJ, "Benzocaine-Induced Methemoglobinemia: Report of a Severe Reaction and Review of the Literature," Ann Pharmacother, 1994, 28(5):643-9.


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