|
| Pronunciation |
 (am
pi SIL in & proe BEN e
sid) |
 |
| U.S. Brand Names |
| Polycillin-PRB®; Probampacin® |
|
| Generic Available |
|
Yes |
|
| Pharmacological Index |
|
Antibiotic, Penicillin |
|
| Use |
|
Uncomplicated infections caused by susceptible strains of Neisseria gonorrhoeae in adults |
|
| Pregnancy Risk Factor |
|
B |
|
| Adverse Reactions |
|
>10%: Central nervous system: Headache Dermatologic: Rash Gastrointestinal: Anorexia, nausea, vomiting, diarrhea, oral candidiasis Neuromuscular & skeletal: Gouty arthritis (acute) 1% to 10%: Cardiovascular: Flushing of face Central nervous system: Dizziness Dermatologic: Skin rash, itching Gastrointestinal: Sore gums, severe abdominal or stomach cramps and pain Genitourinary: Dysuria Renal: Renal calculi <1%: Central nervous system: Seizures Hematologic: Leukopenia, hemolytic anemia, aplastic anemia Hepatic: Hepatic necrosis Renal: Urate nephropathy, nephrotic syndrome Miscellaneous: Anaphylaxis, penicillin encephalopathy, lymphocytic leukemia |
|
| Drug Interactions |
|
Avoid concomitant use with ketorolac since its half-life is increased two-fold and levels and toxicity are significantly increased by probenecid; allopurinol theoretically has an additional potential for ampicillin rash |
|
| Usual Dosage |
|
Administer entire contents of bottle as a single one time dose |
|
| Dental Health: Local Anesthetic/Vasoconstrictor Precautions |
|
No information available to require special precautions |
|
| Dental Health: Effects on Dental Treatment |
|
>10% oral candidiasis after chronic dosing |
|
| Patient Information |
|
Shake well |
|
| Dosage Forms |
|
Powder for oral suspension: Ampicillin 3.5 g and probenecid 1 g per bottle |
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