Look Up > Drugs > Alclometasone
Alclometasone
Pronunciation
U.S. Brand Names
Generic Available
Synonyms
Pharmacological Index
Use
Pregnancy Risk Factor
Contraindications
Warnings/Precautions
Adverse Reactions
Overdosage/Toxicology
Drug Interactions
Stability
Mechanism of Action
Usual Dosage
Mental Health: Effects on Mental Status
Mental Health: Effects on Psychiatric Treatment
Dental Health: Local Anesthetic/Vasoconstrictor Precautions
Dental Health: Effects on Dental Treatment
Patient Information
Nursing Implications
Dosage Forms

Pronunciation
(al kloe MET a sone)

U.S. Brand Names
Aclovate® Topical

Generic Available

No


Synonyms
Alclometasone Dipropionate

Pharmacological Index

Corticosteroid, Topical


Use

Treats inflammation of corticosteroid-responsive dermatosis (low potency topical corticosteroid)


Pregnancy Risk Factor

C


Contraindications

Viral, fungal, or tubercular skin lesions, known hypersensitivity to alclometasone or any component


Warnings/Precautions

Adverse systemic effects may occur when used on large areas of the body, denuded areas, for prolonged periods of time, with an occlusive dressing, and/or in infants or small children


Adverse Reactions

1% to 10%:

Dermatologic: Itching, erythema, dryness papular rashes

Local: Burning, irritation

<1%: Hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, maceration of skin, skin atrophy, striae, miliaria


Overdosage/Toxicology

Symptoms of overdose include cushingoid appearance (systemic), muscle weakness (systemic), osteoporosis (systemic) all with long-term use only. When consumed in excessive quantities for prolonged periods, systemic hypercorticism and adrenal suppression may occur; in those cases, discontinuation and withdrawal of the corticosteroid should be done judiciously.


Drug Interactions

No data reported


Stability

Store between 2°C and 30°C (36°F and 86°F)


Mechanism of Action

Stimulates the synthesis of enzymes needed to decrease inflammation, suppress mitotic activity, and cause vasoconstriction


Usual Dosage

Topical: Apply a thin film to the affected area 2-3 times/day. Therapy should be discontinued when control is achieved; if no improvement is seen, reassessment of diagnosis may be necessary.


Mental Health: Effects on Mental Status

None reported


Mental Health: Effects on Psychiatric Treatment

None reported


Dental Health: Local Anesthetic/Vasoconstrictor Precautions

No information available to require special precautions


Dental Health: Effects on Dental Treatment

No effects or complications reported


Patient Information

Before applying, gently wash area to reduce risk of infection; apply a thin film to cleansed area and rub in gently and thoroughly until medication vanishes; avoid exposure to sunlight, severe sunburn may occur


Nursing Implications

For external use only; do not use on open wounds; apply sparingly to occlusive dressings; should not be used in the presence of open or weeping lesions


Dosage Forms

Cream, as dipropionate: 0.05% (15 g, 45 g, 60 g)

Ointment, topical, as dipropionate: 0.05% (15 g, 45 g, 60 g)


Copyright © 1978-2000 Lexi-Comp Inc. All Rights Reserved