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Pronunciation |
|
(al
kloe MET a
sone) |
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U.S. Brand
Names |
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Aclovate®
Topical |
|
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Generic
Available |
|
No |
|
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Synonyms |
|
Alclometasone Dipropionate |
|
|
Pharmacological Index |
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Corticosteroid, Topical |
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|
Use |
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Treats inflammation of corticosteroid-responsive dermatosis (low potency
topical corticosteroid) |
|
|
Pregnancy Risk
Factor |
|
C |
|
|
Contraindications |
|
Viral, fungal, or tubercular skin lesions, known hypersensitivity to
alclometasone or any component |
|
|
Warnings/Precautions |
|
Adverse systemic effects may occur when used on large areas of the body,
denuded areas, for prolonged periods of time, with an occlusive dressing, and/or
in infants or small children |
|
|
Adverse
Reactions |
|
1% to 10%:
Dermatologic: Itching, erythema, dryness papular rashes
Local: Burning, irritation
<1%: Hypertrichosis, acneiform eruptions, hypopigmentation, perioral
dermatitis, maceration of skin, skin atrophy, striae, miliaria
|
|
|
Overdosage/Toxicology |
|
Symptoms of overdose include cushingoid appearance (systemic), muscle
weakness (systemic), osteoporosis (systemic) all with long-term use only. When
consumed in excessive quantities for prolonged periods, systemic hypercorticism
and adrenal suppression may occur; in those cases, discontinuation and
withdrawal of the corticosteroid should be done
judiciously. |
|
|
Drug
Interactions |
|
No data reported |
|
|
Stability |
|
Store between 2°C and 30°C
(36°F and 86°F) |
|
|
Mechanism of
Action |
|
Stimulates the synthesis of enzymes needed to decrease inflammation, suppress
mitotic activity, and cause vasoconstriction |
|
|
Usual Dosage |
|
Topical: Apply a thin film to the affected area 2-3 times/day. Therapy should
be discontinued when control is achieved; if no improvement is seen,
reassessment of diagnosis may be necessary. |
|
|
Mental Health: Effects
on Mental Status |
|
None reported |
|
|
Mental Health:
Effects on Psychiatric
Treatment |
|
None reported |
|
|
Dental Health: Local
Anesthetic/Vasoconstrictor
Precautions |
|
No information available to require special precautions |
|
|
Dental Health:
Effects on Dental Treatment |
|
No effects or complications reported |
|
|
Patient
Information |
|
Before applying, gently wash area to reduce risk of infection; apply a thin
film to cleansed area and rub in gently and thoroughly until medication
vanishes; avoid exposure to sunlight, severe sunburn may
occur |
|
|
Nursing
Implications |
|
For external use only; do not use on open wounds; apply sparingly to
occlusive dressings; should not be used in the presence of open or weeping
lesions |
|
|
Dosage Forms |
|
Cream, as dipropionate: 0.05% (15 g, 45 g, 60 g)
Ointment, topical, as dipropionate: 0.05% (15 g, 45 g, 60 g)
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