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Overview |
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Definition |
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Irritable bowel syndrome (IBS) presents itself as a variety of lower
abdominal symptoms, including pain, cramping, gassiness, and either or both
diarrhea and constipation. Symptoms often appear after eating or during stress
and result from abnormal motility. Because the gastrointestinal tract is
particularly sensitive to stimuli, the effect of stress, diet, drugs, hormones,
and minor irritants can aggravate its tendency to contract abnormally.
The syndrome generally takes two forms. Spastic colon, often triggered by
eating a meal, produces periods of constipation, diarrhea, or both, along with
abdominal pain. Painless diarrhea comes on urgently, generally during or after a
meal, or on waking after a night's sleep.
IBS often starts in young adulthood. Between 10% and 20% of the population
has symptoms of the syndrome at some time. It accounts for half of all
gastrointestinal referrals, and is a major cause of lost work or school time. It
affects twice as many women as men. Some women show more symptoms during
menstruation. |
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Etiology |
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No underlying anatomic or definitive etiologic cause has emerged. The
symptoms result from abnormal motility, and the contractions become
disorganized, harsh, or spasmodic. The erratic propulsion that results can cause
sudden, explosive elimination of stools, or can delay any elimination. Chronic
stress or depression often trigger attacks. Eating in general can cause
immediate need for a bowel movement. Specific foods such as high-fat meals,
wheat, dairy products, and citrus fruits, as well as drinks containing caffeine
or alcohol, can aggravate the condition. |
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Risk Factors |
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- Stress
- Depression
- In some cases, eating specific foods, including wheat, dairy
products, or citrus fruits
- In some cases, alcohol or caffeine
- Familial predisposition
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Signs and Symptoms |
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- Crampy pain in the lower abdomen
- Bloating
- Gassiness
- Changes in bowel habits
- Diarrhea or constipation, or both alternately
- Need for bowel movement immediately on waking or after
eating
- Relief of pain after bowel movement
- Feeling of incomplete emptying after bowel movement
- Mucus in feces
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Differential
Diagnosis |
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- Inflammatory bowel diseases (ulcerative colitis or Crohn's
disease)
- Diverticulosis
- Duodenal ulcer
- Lactose intolerance
- Biliary tract disease
- Abuse of cathartics
- Amebiasis, giardiasis, or other parasitic disease
- Campylobacter enteritis
- Allergic gastroenteropathy
- Colonic polyps
- Colonic neoplasms
- Ischemic enteropathy (in patients over age 60)
- Ovarian neoplasms and cysts
- Uterine fibroids
- Hyperthyroidism
- Infections
- Diabetes mellitus
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Diagnosis |
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Physical Examination |
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Patients with either form of IBS usually appear in good health. Palpation of
the abdomen may show tenderness. Rectal examination often indicates a rectum
that is empty or contains hard, firm feces. A pelvic examination of women serves
to eliminate alternative diagnoses. |
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Laboratory Tests |
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- A stool sample—preferably a three-day slide
series—can reveal the presence of blood, ova, parasites
or bacteria.
- Biochemical profiling, including serum amylase, and urinalysis, also
serves to narrow the diagnosis—ESR,
CBC.
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Imaging |
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Abdominal ultrasound, a barium enema X ray, X rays of the small bowel or the
upper gastrointestinal tract, and colonoscopy can also help to rule out organic
causes of IBS-like symptoms. |
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Other Diagnostic
Procedures |
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Sigmoidoscopy, particularly with a flexible instrument, shows the state of
the colon up to 60 centimeters, the area in which 65% to 70% of colonic
neoplasms and polyps are found. In cases of IBS, this procedure often triggers
spasm and pain, but shows no abnormalities. |
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Treatment Options |
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Treatment Strategy |
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Sympathetic understanding plays a major role in treatment. Explain the nature
of the condition, and assure the patient that he or she has no major underlying
organic disease. Outline the extreme sensitivity of the patient's bowels to
stimuli such as stress, food, drugs, and hormones. Remember that no two IBS
patients are alike. Encourage patients to avoid, wherever possible, stressful
situations that may trigger episodes of IBS. |
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Drug Therapies |
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- Oral doses of antispasmodic agents such as hyoscyamine (Anaspaz,
Cytospaz, Levsin) or dicyclomine (Bentyl, Bemote, Di-Spaz) can reduce the pain
of spasm. They should be taken 30 to 60 minutes before meals. Oral doses of
amitriptyline, taken 30 to 60 minutes before meals, reduce depression and bowel
spasms.
- Bulk-producing agents (psyllium, as in Metamucil) or antiflatulents
(simethicone, as in Mylicon) as symptoms indicate
- Lactose capsules for lactose intolerance, as indicated
- Patients with diarrhea should take loperamide (as in Imodium) before
meals, as needed.
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Complementary and Alternative
Therapies |
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Irritable bowel syndrome is a multifactoral condition that can often be
successfully treated with alternative therapies. Most important are proper
eating habits, stress reduction, and gastrointestinal support. Incorporating
nutritional supplements may help reduce the effects of stress. Intestinal
support can include fiber, acidophilus, peppermint oil capsules, or a tea of
fennel or ginger. Chronic IBS may also respond to digestive enzymes and a
supportive tincture. Stress reduction techniques through biofeedback, hypnosis,
or counseling can help patients to deal with stress. |
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Nutrition |
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- Removal of known food allergens or food irritants is imperative. The
most common food allergens are dairy, wheat, corn, peanuts, citrus, soy, eggs,
fish, and tomatoes. An elimination/challenge trial may be helpful in uncovering
sensitivities. Remove all suspected allergens from the diet for two weeks. Add
in one food every three days and wait for reaction which may include digestive
upset, headache, fatigue, flushing, or worsening of symptoms.
- Fiber supplementation helps reduce abdominal pain, cramping, and gas.
Supplements include psyllium, flaxmeal, slippery elm (Ulmus fulva)
powder, marshmallow root (Althaea officinalis) powder.
- Digestive enzymes taken 20 minutes before meals can help enhance
digestion and normalize bowel function.
- One teaspoon of raw bran with each meal, supplemented by extra
fluids, provides fiber reliably.
- Pro-flora supplements such as acidophilus and lactobacillus species
taken bid to tid can help to rebalance normal bowel flora and reduce gas and
bloating.
- Magnesium (200 mg bid to tid) and B-complex (50 to 100 mg/day) with
extra B5 (pantothenic acid; 100 mg/day) may help to reduce the effects of
stress.
- Low-fat diets may relieve abdominal pain following meals. Patients
with spasm and constipation often benefit from dietary fiber
supplementation.
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Herbs |
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Ascertain a diagnosis before pursuing treatment. Herbs may be used as dried
extracts (capsules, powders, teas), glycerites (glycerine extracts), or
tinctures (alcohol extracts). Unless otherwise indicated, teas should be made
with 1 tsp. herb per cup of hot water. Steep covered 5 to 10 minutes for leaf or
flowers, and 10 to 20 minutes for roots. Drink 2 to 4 cups/day. Tinctures may be
used singly or in combination as noted.
- Enteric-coated peppermint oil (Mentha piperita): one to two
capsules (0.2 ml peppermint oil/capsule) tid after meals. Peppermint oil is a
potent spasmolytic that reduces bowel irritability.
- A tea of fennel seed (Foeniculum vulgare) or ginger root
(Zingiber officinale) taken after meals promotes elimination of
intestinal gas and good digestion.
- A tincture of equal parts of the following herbs may be taken before
meals (30 drops tid): valerian (Valeriana officinalis), passionflower
(Passiflora incarnata), anise seed (Pimpinella anisum) extract,
meadowsweet (Filipendula ulmaria), wild yam (Dioscorea villosa),
and milk thistle (Silybum marianum). Combined, they enhance
digestion, relieve spasm, and reduce
inflammation.
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Homeopathy |
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An experienced homeopath should assess individual constitutional types and
severity of disease to select the correct remedy and
potency. |
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Physical Medicine |
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- Electric heating pads, hot water bottles, and long hot baths can
relieve painful spasms and cramping in the abdomen.
- Regular exercise, such as walking, can reduce stress, and encourages
bowel movements in constipated individuals.
- Castor oil pack. Used externally, castor oil is a powerful
anti-inflammatory. Apply oil directly to skin, cover with a clean soft cloth
(e.g., flannel) and plastic wrap. Place a heat source (hot water bottle or
heating pad) over the pack and let sit for 30 to 60 minutes. For best results,
use for three consecutive days.
- Abdominal breathing helps to induce the relaxation response and may
aid normal physiological functioning (e.g., digestion). Chewing food thoroughly
enhances digestion. Enzyme release begins in the
mouth.
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Acupuncture |
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Acupuncture can be useful in reducing frequency and duration of IBS episodes
as well as providing overall support to gastrointestinal
function. |
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Massage |
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Therapeutic massage may be beneficial in reducing the effects of stress and
increasing the overall sense of well-being. |
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Patient Monitoring |
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Insist on regular follow-up visits, to ensure that symptoms remain under
control, and to detect any possible organic diseases of the gastrointestinal
tract. Make patients aware that they may suffer episodes of abdominal symptoms
related to psychologic stress and depression. |
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Other
Considerations |
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Prevention |
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Best to develop pattern of regular exercise, to reduce stress and aid GI
motility. A diet generally higher in fiber and lower in
fat. |
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Complications/Sequelae |
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Depression or anxiety associated with unresolved
symptoms |
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Prognosis |
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Recurrences throughout life, particularly at times of high stress or relaxed
preventative measures |
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Pregnancy |
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Pregnancy may exacerbate symptoms of IBS. Treatment must be supervised by an
experienced practitioner. |
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References |
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Berkow R, ed. Merck Manual of Diagnosis and Therapy. 16th ed. Rahway,
NJ: The Merck Publishing Group; 1992.
Dambro MR, ed. Griffith's 5 Minute Clinical Consult. New York, NY:
Lippincott, Williams and Wilkins; 1998.
Koch TR. Peppermint oil and irritable bowel syndrome [In Process Citation].
Am J Gastroenterol. 1998;93:2304-2305.
Liu JH, Chen GH, Yeh HZ, Huang CK, Poon SK. Enteric-coated peppermint-oil
capsules in the treatment of irritable bowel syndrome: a prospective, randomized
trial. J Gastroenterol. 1997;32:765-768.
Murray MT, Pizzorno JE. Encyclopedia of Natural Medicine. 2nd ed.
Rocklin, Calif: Prima Publishing; 1998:396-400.
Pittler MH, Ernst E. Peppermint oil for irritable bowel syndrome: a critical
review and metaanalysis. Am J Gastroenterol.
1998;93:1131-1135. |
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Copyright © 2000 Integrative Medicine
Communications This publication contains
information relating to general principles
of medical care that should not in any event be construed as specific
instructions for individual patients. The publisher does not accept any
responsibility for the accuracy of the information or the consequences arising
from the application, use, or misuse of any of the information contained herein,
including any injury and/or damage to any person or property as a matter of
product liability, negligence, or otherwise. No warranty, expressed or implied,
is made in regard to the contents of this material. No claims or endorsements
are made for any drugs or compounds currently marketed or in investigative use.
The reader is advised to check product information (including package inserts)
for changes and new information regarding dosage, precautions, warnings,
interactions, and contraindications before administering any drug, herb, or
supplement discussed herein. | |