Saint John's Wort

PharmakonPharmakon عضو ذهبي
تم تعديل 2010/08/24 في الطب البديل Alternative Medicine

Saint John's Wort is an outstanding herbal remedy steeped in many folk legends and traditions of

The Greek name for this plant is Hypericum (also its Latin botanical name), which means "over a spirit." It was so named because it was believed to provide special protection, particularly during the summer months, when there is a tendency to feel overly expanded and adversely affected by heat and light. Later, it was associated with St. John the Baptist, regarded as a great solar adept within the Essene tradition, and whose feast day is commemorated at high summer. Despite the great spiritual
power of St. John the Baptist, he pointed to the Christ as the very source of the Sun.

St John's wort is widely known as a herbal treatment for depression. In some countries, such as Germany, it is commonly prescribed for mild depression, especially in children, adolescents, and where cost is a concern

The exact mechanism by which St John's wort functions is unclear and subject to conjecture. The St John's wort mechanism is believed to involve inhibition of serotonin (5-HT) reuptake, much like the conventional selective serotonin reuptake inhibitor (SSRI) antidepressants. The major active antidepressive constituents in St John's wort are thought to be hyperforin and hypericin, although other biologically active constituents present, for example, flavonoids and tannins

Some believe that hyperforin is the major constituent responsible for antidepressant activity, and it has been shown to inhibit the uptake of 5-HT, dopamine, and noradrenaline. Hyperforin also has affinity for GABA and glutamate receptors. On the other hand, a hyperforin-free extract of St John's wort may still have significant antidepressive effects

When analyzed bio-chemically, the St. John's Wort is found to contain significant amounts of hypericin, a photosensitizing substance that reacts with the light to cause skin burns in light-skinned persons.


  • dr.Hazemdr.Hazem مدير عام
    تم تعديل 2010/08/23
    طيب دكتورة فارما هل هذه النبتة تستعمل كخلاصة او لها مستحضر صيدلاني ضمن الصيدلية ؟!
  • PharmakonPharmakon عضو ذهبي
    تم تعديل 2010/08/24
    . most commercially available preparations of Hpericum in united states are dreid alcholic extracts in a solid oral dosage form

    Other preparations include the dried herb , teas , tinctures or liquid extract

    اكيد يوجد منها ادويه ف الصيدليه .... لكن جارى البحث عن brand names
  • PharmakonPharmakon عضو ذهبي
    تم تعديل 2010/08/24
    Standardized extracts are generally available over the counter, though in some countries (such as Ireland) a prescription is required. Extracts are usually in tablet or capsule form, and also in teabags and tinctures. Herbalists are more likely to use a fluid extract than a tincture.
  • dr.Hazemdr.Hazem مدير عام
    تم تعديل 2010/08/24
    شكراً على الرد دكتورة ..