Pregnancy: (Category C / D if used in 2nd or 3rd trimesters)
manifests both beta1 and beta 2 adrenergic blocking activity.
ý Angina pectoris.
ý Cardiac arrhythmias.
ý Prophylaxis of migrin.
ý Prophylaxis of MI.
ý by mouth, hypertension, initially 80 mg twice daily, increased at weekly intervals as required; maintenance 160–320 mg daily
ý Angina, initially 40 mg 2–3 times daily; maintenance 120–240 mg daily
ý Arrhythmias, hypertrophic obstructive cardiomyopathy, anxiety tachycardia, and thyrotoxicosis (adjunct), 10–40 mg 3–4 times daily
ý Anxiety with symptoms such as palpitations, sweating, tremor, 40 mg once daily, increased to 40 mg 3 times daily if necessary
ý Prophylaxis after myocardial infarction, 40 mg 4 times daily for 2–3 days, then 80 mg twice daily, beginning 5 to 21 days after infarction
ý Migraine prophylaxis and essential tremor, initially 40 mg 2–3 times daily; maintenance 80–160 mg daily
ý By intravenous injection, arrhythmias and thyrotoxic crisis, 1 mg over 1 minute; if necessary repeat at 2-minute intervals; max. 10 mg (5 mg in anesthesia)
Bradycardia, C.H.F., cardiogenic shock, diabetes, thyrotoxicosis, chronic bronchitis, asthma, bronchospasm, emphysema.
Bradycardia, C.H.F., hypotension, cold extremities (due to peripheral vasoconstriction), edema, dyspnia, shortness of breath, nausea, vomiting, hepatomegaly and bronchospasm.
v Instruct patient/family to take blood pressure and pulse.
v Provide written instructions as when to call physician (e.g. HR below 50 beat/min).
v Consult the physician before interrupting the therapy.
v Some drugs lead to blurring of vision, so that tell patients not to engage in activities need mental alertness.
v Instruct patient to dress warmly during cold weather.
v Diabetic patient should be very careful about symptoms of hypoglycemia.
v Report any asthma-like symptoms.