dr.joandr.joan عضو ماسي
تم تعديل 2009/07/02 في أدوية الطوارئ Emergency drugs
Nefidipine :
Trade names: Pressolat, Adalat
Class: calcium channel blocking agent (anti-angina, antihypertensive).
Pregnancy: (Category C)
These agents inhibit the influx of calcium through the cell membrane resulting in a depression of automatically and conduction velocity in both smooth and cardiac muscles leading to:
1. Myocardial contractility. .
2. Inhibit spasm of coronary arteries dilatation.
3. Peripheral vasodilatation peripheral resistance.
4. S. A. node automatically and conduction heart rate.
vasospastic angina, essential hypertension
Raynaud's phenomenon, initially 5 mg 3 times daily, adjusted according to response to 20 mg 3 times daily ,angina prophylaxis not recommended, Hypertension, not recommended modified release : hypertension, 20–30 mg once daily, increased if necessary; max. 90 mg once daily , Angina prophylaxis, 30 mg once daily, increased if necessary; max. 90 mg once daily
hypersensitivity, lactation
Side effects:
  • pulmonary and peripheral edema
  • hypotension
  • headache
  • upset stomach
  • dizziness or lightheadedness
  • excessive tiredness
  • flushing (feeling of warmth)
  • heartburn
  • Tachycardia
  • muscle cramps
  • enlargement of gum tissue around teeth
  • constipation
  • nasal congestion
  • cough
  • decreased sexual ability
Nursing considerations:
  • Discuss with the patient/family the goals of therapy.
  • Teach them how to take pulse and blood pressure. Hold the medication in case of hypotension or bradycardia and consult the treating Dr.
  • Instruct the client to report any untoward sings as dizziness.
  • In case of postural hypotension, advise the client to change position.
  • Advise client to sit down immediately if fainting occurs.
Calcium antagonists should be taken with meals to GI irritation