Gentamycin

dr.joandr.joan عضو ماسي
تم تعديل 2009/06/28 في أدوية الطوارئ Emergency drugs
Gentamycin :
Trade name: Garamyein.
Class: - antibiotic, aminoglycoside.
Pregnancy: (Category C)

Indication:
v It is the drug of choice for hospital- acquired gram negative
sepsis including neonatal sepsis.
v Serious staphylococcal infections.
Side effects
§ blood pressure, alopecia
§ CNS: ototoxicity, tinnitus, dizziness, ringing in the ears, vertigo.
§ GI: nausea, vomiting, anorexia, weight loss, increased salivation.
§ C.V.: palpitation, hypotension or hypertension.
§ Hematologic: Decrease number of blood cells.
§ GU: nephrotoxicity
§ Local: Pain and irritation at IM injection site.
Formulation:-
Vial 2 ml containing 20 mg.
Ampoule 2 ml containing 80 mg.
Dosage:-
v I.M. (usual). I.V. adults 3 mg\kg q 8 hr up to 5 mg\kg daily.
Children 2-2.5 mg\kg q 8 hr.
Newborns 2.5 mg\ kg q 12 hr.
Ophthalmic solution 0.3%, 1-2 drops q 15-30 minutes.
Topical ointment 0.1%, 1-5 times daily to the affected area.
Streptococcal or enterococcal endocarditis in combination with other drugs, 80 mg twice daily.
N.B.:-
Should not be mixed with other drugs for parenteral use.
Nursing implication:
§ When given IM, give it slowly and deep in the muscle.
§ Dilute dose when given IV.
§ Monitor for kidney function tests, complete blood count when used for more than 7 days. Consult with Dr. accordingly.