Ceftazidime

dr.joan

Ceftazidime :
Trade name: Ceptaz, Fortum, Tazicef, Tazidime
Class: Antibiotic "cephalosporines" third-generation
Pregnancy: (Category

Action : Bind to bacterial cell wall membrane, causing cell death.
Uses:

Ceftazidime eliminates bacteria that cause many kinds of infections, including lung, skin, bone, joint, stomach, blood, gynecological, and urinary tract infections

Dose
by deep intramuscular injection or intravenous injection or infusion, 1 g every 8 hours or 2 g every 12 hours; 2 g every 8–12 hours or 3 g every 12 hours in severe infections; single doses over 1 g intravenous route only; elderly usual max. 3 g daily; child up to 2 months 25–60 mg/kg daily in 2 divided doses, over 2 months 30–100 mg/kg daily in 2–3 divided doses; up to 150 mg/kg daily (max. 6 g daily) in 3 divided doses if immuno- compromised or meningitis; intravenous route recommended for children
Urinary-tract and less serious infections, 0.5–1 g every 12 hours
Pseudomonal lung infection in cystic fibrosis, adult 100–150 mg/kg daily in 3 divided doses; child up to 150 mg/kg daily (max. 6 g daily) in 3divided doses; intravenous route recommended for children
Surgical prophylaxis, prostatic surgery, 1 g at induction of anesthesia repeated if necessary when catheter removed
Contraindications:
· Hypersensitivity to cephalosporin

Side effects:
· Diarrhea, stomach pain, upset stomach, vomiting.
Nursing considerations:

• Infuse over 30 minutes unless otherwise indicated.
• Therapy should be continued for at least 2-3 days after symptoms of infection have disappeared.
• Assess client with a history of hypersensitivity reaction. “for penicillin or cephalosporin.”
• Assess client financial status. These drugs are usually expensive.
• Obtain liver & renal studies.