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Interactions
with Ginseng, Siberian | |
Digoxin
Siberian ginseng reportedly elevated synthetic digoxin drug levels causing no
toxic effects (McRae 1996). The mechanism for this apparent interaction may be
conversion in vivo of a component of ginseng to digoxin, interference with
digoxin elimination, or digoxin assay. However, based on previously documented
adulteration, it is possible that the commercial E. senticosus product
used was actually Periploca sepium, which is known to
contain cardiac glycosides (Awang 1996). |
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References |
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Awang DVC. Siberian ginseng toxicity may be a case of mistaken identity.
Can Med Assoc J. 1996;155(9):1237.
McRae S. Elevated serum digoxin levels in a patient taking digoxin and
Siberian ginseng. Can Med Assoc J.
1996;155:293-295. |
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