Ginseng, Siberian
  Uses of this Herb
Anorexia Nervosa
Atherosclerosis
Chronic Fatigue Syndrome
Rheumatoid Arthritis
Stress
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  Drugs that Interact
Summary
Digoxin
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Western Herbalism
Look Up > Herbs > Ginseng, Siberian > Interactions
Interactions with Ginseng, Siberian
Digoxin

Siberian ginseng reportedly elevated synthetic digoxin drug levels causing no toxic effects (McRae 1996). The mechanism for this apparent interaction may be conversion in vivo of a component of ginseng to digoxin, interference with digoxin elimination, or digoxin assay. However, based on previously documented adulteration, it is possible that the commercial E. senticosus product used was actually Periploca sepium, which is known to contain cardiac glycosides (Awang 1996).


References

Awang DVC. Siberian ginseng toxicity may be a case of mistaken identity. Can Med Assoc J. 1996;155(9):1237.

McRae S. Elevated serum digoxin levels in a patient taking digoxin and Siberian ginseng. Can Med Assoc J. 1996;155:293-295.


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