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Pronunciation |
|
(trye
dye heks ETH
il) |
|
|
U.S. Brand
Names |
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Pathilon® |
|
|
Generic
Available |
|
No |
|
|
Synonyms |
|
Tridihexethyl Chloride |
|
|
Pharmacological Index |
|
Anticholinergic Agent; Antispasmodic Agent,
Gastrointestinal |
|
|
Use |
|
Adjunctive therapy in peptic ulcer treatment |
|
|
Pregnancy Risk
Factor |
|
C |
|
|
Contraindications |
|
Glaucoma; obstructive uropathy (ie, bladder neck obstruction secondary to
prostatic hypertrophy); obstructive disorders of GI tract (ie, achalasia,
paralytic ileus, pyloroduodenal stenosis); intestinal atony (elderly or
debilitated patients); acute hemorrhage with unstable cardiovascular status;
ulcerative colitis that is severe or complicated by toxic megacolon; myasthenia
gravis |
|
|
Adverse
Reactions |
|
>10%:
Dermatologic: Dry skin
Gastrointestinal: Constipation, xerostomia, dry throat
Respiratory: Dry nose
Miscellaneous: Decreased diaphoresis
1% to 10%: Gastrointestinal: Dysphagia |
|
|
Drug
Interactions |
|
Potassium chloride wax-matrix preparations |
|
|
Usual Dosage |
|
Adults: Oral: 1-2 tablets 3-4 times/day before meals and 2 tablets at
bedtime |
|
|
Dietary
Considerations |
|
Should be administered 30 minutes before meals and at
bedtime |
|
|
Mental Health: Effects
on Mental Status |
|
May rarely cause drowsiness, confusion, nervousness, amnesia, or
insomnia |
|
|
Mental Health:
Effects on Psychiatric
Treatment |
|
Concurrent use with psychotropics may produce additive sedation or dry
mouth |
|
|
Dental Health: Local
Anesthetic/Vasoconstrictor
Precautions |
|
No information available to require special precautions |
|
|
Dental Health:
Effects on Dental Treatment |
|
>10% of patients experience dry mouth |
|
|
Patient
Information |
|
Take 30 minutes before meals and at bedtime; maintain good oral hygiene
habits, because lack of saliva may increase chance of cavities; observe caution
while driving or performing other tasks requiring alertness, as drug may cause
drowsiness, dizziness, or blurred vision; notify physician if skin rash,
flushing or eye pain occurs; or if difficulty in urinating, constipation, or
sensitivity to light becomes severe or persists |
|
|
Nursing
Implications |
|
Maintain good oral hygiene habits, because lack of saliva may increase chance
of cavities; observe caution while driving or performing other tasks requiring
alertness, as drug may cause drowsiness, dizziness, or blurred vision; notify
physician if skin rash, flushing or eye pain occurs; or if difficulty in
urinating, constipation, or sensitivity to light becomes severe or
persists |
|
|
Dosage Forms |
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Tablet, as chloride: 25 mg |
|
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