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Pronunciation |
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(loe
DOKS a mide troe METH a
meen) |
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U.S. Brand
Names |
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Alomide®
Ophthalmic |
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Generic
Available |
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No |
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Pharmacological Index |
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Mast Cell Stabilizer |
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|
Use |
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Treatment of vernal keratoconjunctivitis, vernal conjunctivitis, and vernal
keratitis |
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Pregnancy Risk
Factor |
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B |
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Contraindications |
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Hypersensitivity to any component of product |
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Warnings/Precautions |
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Safety and efficacy in children <2 years of age have not been established;
not for injection; not for use in patients wearing soft contact lenses during
treatment |
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Adverse
Reactions |
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>10%: Local: Transient burning, stinging, discomfort
1% to 10%:
Central nervous system: Headache
Ocular: Blurred vision, corneal erosion/ulcer, eye pain, corneal abrasion,
blepharitis
<1%: Dizziness, somnolence, rash, nausea, stomach discomfort, sneezing,
dry nose |
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Overdosage/Toxicology |
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Symptoms include feeling of warmth of flushing, headache, dizziness, fatigue,
sweating, nausea, loose stools, and urinary frequency/urgency; consider emesis
in the event of accidental ingestion |
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Drug
Interactions |
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No data reported |
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Mechanism of
Action |
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Mast cell stabilizer that inhibits the in vivo type I immediate
hypersensitivity reaction to increase cutaneous vascular permeability associated
with IgE and antigen-mediated reactions |
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Pharmacodynamics/Kinetics |
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Absorption: Topical: Very small and undetectable |
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Usual Dosage |
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Children >2 years and Adults: Instill 1-2 drops in eye(s) 4 times/day for
up to 3 months |
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Mental Health: Effects
on Mental Status |
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May cause drowsiness or dizziness |
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Mental Health:
Effects on Psychiatric
Treatment |
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None reported |
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Dental Health: Local
Anesthetic/Vasoconstrictor
Precautions |
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No information available to require special precautions |
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Dental Health:
Effects on Dental Treatment |
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No effects or complications reported |
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Patient
Information |
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Do not wear soft contact lenses during treatment |
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Dosage Forms |
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Solution, ophthalmic: 0.1% (10
mL) |
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