Bacitracin, Neomycin, and Polymyxin B

Interactions with supplements

Vitamin A (Retinol)

Vitamin B3 (Niacin)

Look Up > Drugs > Bacitracin, Neomycin, and Polymyxin B

	Pronunciation
	U.S. Brand Names
	Generic Available
	Canadian Brand Names
	Synonyms
	Pharmacological Index
	Use
	Pregnancy Risk Factor
	Contraindications
	Adverse Reactions

	Drug Interactions
	Mechanism of Action
	Usual Dosage
	Mental Health: Effects on Mental Status
	Mental Health: Effects on Psychiatric Treatment
	Dental Health: Local Anesthetic/Vasoconstrictor Precautions
	Dental Health: Effects on Dental Treatment
	Patient Information
	Nursing Implications
	Dosage Forms

Pronunciation

(bas i TRAY sin, nee oh MYE sin & pol i MIKS in bee)

U.S. Brand Names

AK-Spore® Ophthalmic Ointment; Medi-Quick® Topical Ointment [OTC]; Mycitracin® Topical [OTC]; Neomixin® Topical [OTC]; Neosporin® Ophthalmic Ointment; Neosporin® Topical Ointment [OTC]; Ocutricin® Topical Ointment; Septa® Topical Ointment [OTC]; Triple Antibiotic® Topical

Generic Available

Yes

Canadian Brand Names

Neotopic

Synonyms

Neomycin, Bacitracin, and Polymyxin B; Polymyxin B, Bacitracin, and Neomycin

Pharmacological Index

Antibiotic, Ophthalmic; Antibiotic, Topical

Use

Helps prevent infection in minor cuts, scrapes and burns; short-term treatment of superficial external ocular infections caused by susceptible organisms

Pregnancy Risk Factor

Contraindications

Hypersensitivity to neomycin, polymyxin B, or zinc bacitracin; epithelial herpes simplex keratitis; mycobacterial or fungal infections; topical ointments for external use only

Adverse Reactions

1% to 10%:

Dermatologic: Reddening, allergic contact dermatitis

Local: Itching, failure to heal

Drug Interactions

No data reported

Mechanism of Action

Refer to individual monographs for Bacitracin; Neomycin Sulfate; and Polymyxin B Sulfate

Usual Dosage

Children and Adults:

Topical: Apply 1-5 times/day to infected area and cover with sterile bandage as needed

Mental Health: Effects on Mental Status

None reported

Mental Health: Effects on Psychiatric Treatment

None reported

Dental Health: Local Anesthetic/Vasoconstrictor Precautions

No information available to require special precautions

Dental Health: Effects on Dental Treatment

No effects or complications reported

Patient Information

See individual agents. Pregnancy/breast-feeding precautions: Inform prescriber if you are or intend to be pregnant. Consult prescriber if breast-feeding.

Nursing Implications

Symptoms of neomycin sensitization include itching, reddening, edema, failure to heal; ophthalmic ointments may retard corneal healing

Dosage Forms

Ointment:

Topical: Bacitracin 400 units, neomycin sulfate 3.5 mg, and polymyxin B sulfate 5000 units per g